Extraskeletal ewing sarcoma : a case report /

Extraskeletal ewing sarcoma : a case report / Angela Rose T. Real. - Fairview, Quezon City: Department of Child Heath, FEU-NRMF, 2008. - 32 pages: tables; (in folder)

Includes appendices and bibliographical references.

Abstract: JP a 4 year old male was admitted due to low back pain for 7 days with associated weakness of both lower extremities following an apparent fall from a four free truck. Spinal cord injury secondary to trauma was the primary consideration. Complete blood count with platelet count, urinalysis, serum electrolytes and x-ray of the knee and pelvis were all normal. ASO determination was positive and erythrocyte sedimetation rate were elevated. Despite giving Gabapentin, Vit B complex and prednisolone, there was progression of symptoms with subsequent development of hyperesthesia and difficulty of urination and defecation. MRI of the thoracolumbosacral area revealed a mass from L1 to L3 hence emergency laminectomy was done revealing a reddish-brown extradural mass from T-12m to L12. Dexamethasone, Ranitide , Ceftazidime, Oxacillin and Amikacin were given. Frozen biopsy of the mass revealed round cell malignancy suggestive of Ewing sarcoma and lymphoma. A bone marrow aspiration biopsy showed metastatic malignancy with small round cell tumor most compatible with extra skeletal Ewing Sarcoma/PNET a rare variant of Ewing sarcoma. In patient having this tumor with metastasis, the prognosis is low (10-25%) After undergoing operation, J.P. developed lymphadenopathies with a gradually growing left upper quadrant mass and persistent anemia and hypoalbuminemia. Whole abdominal ultrasound revealed retroperitoneal mass. and bone marrow biopsy revealed metastatic malignancy. Despite aggressive treatment and management, the patient deteriorated and succumbed.

Research - Department of Child Health

CH 2008 0003