Histologic effects of ginglo biloba on the liver and gall bladder and on the weight of mus musculus /

Histologic effects of ginglo biloba on the liver and gall bladder and on the weight of mus musculus / Jyn E. Aragon, Christine Baliwang, Buena Marie Brana, Jenifer Buson, Christine Ferranculo, Adelle Florendo, Anna Marie Gallego, Liza Gonzales, Jason Hermosado, Christine Joy Lacar, Joanne Lara, Nesmarie Manalo, Vincent Paolo Rugay, Rey Vincent Triunfante, and Lejani Uycorrea. - Fairview, Quezon City: Department of Human Structural Biology, FEU-NRMF, 2005. - 40 pages: illustrations, tables, photos; 30 cm.

Includes appendices and bibliographical references.

Abstract: G. biloba extract (GBE) was fed to the mice, in proportion to their individual body weight. The mice was subdivided into a control group (TI), normal (T@), and a high-dosage (T#) group. The anatomical alterations and tissue alteration of the liver among these groups were compared. There was no significant difference between the anatomical features of the high and low dosage, as compared to the control group. There, were, however, prominent pigmentation on the experimental groups (T2 and T3). This was attributed to the oxidation of the proanthocyanidins. The presence of bloated and very yellowish gall bladders in both the high and low dosage groups was also was also noted. This observations was attributed to increase in cholesterol processing as induced by the extract. It was also observed that the mice in the experimental groups, fed with the extract, manifested a decrease in weight. This was attributed to the flavonoid component of the G. biliba extract. The normal tissue livers of the experimental groups show low toxicity level of the G. biloba. GBE does not directly affect the functions of the liver.

Thesis - Department of Human Structural Biology

M HSB 2005 0009