Ewing Sarcoma: The Diagnostic Dilemma (Record no. 10062)

MARC details
000 -LEADER
fixed length control field 02415nam a22001937a 4500
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152920.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170804b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title ENGLISH
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number RESRAD20160006
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Ayuyao, Eunice Mae J., M.D.
245 ## - TITLE STATEMENT
Title Ewing Sarcoma: The Diagnostic Dilemma
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. QUEZON CITY
Name of publisher, distributor, etc. FEU-NRMF
Date of publication, distribution, etc. AUGUST 2016
300 ## - PHYSICAL DESCRIPTION
Extent 14 PAGES
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT: Ewing sarcoma (ES) is the second most common primary malignant pediatric bone neoplasm, [1] however, cranial occurrence is extremely rare. [2] The following is a discussion about such a case in 4 year-old child who presented with right ptosis, headache, visual disturbance and eye movement abnormality initially suspected to be a case of meningioma. Prompt diagnosis and treatment is crucial in ES because once metastasis is detected, poor prognosis follows with survival rate of only up to 30%. In this case, ES may have been overlooked at the onset of the investigation of the patient's condition because 1) her clinical presentation was nonspecific for intracranial tumors with mass effect, 2) MRI and CT findings were not the most typical for this malignancy and 3) biopsy findings were vaguely congruent with meningioma, which was the primary consideration early on. However, since the morphology of the excised tumor was still not the most typical for meningioma, it is prudent to consider other differentials and probe further Immunohistochemical staining was thus done and showed results diffusely positive for CD99 and synaptophysin, and focally positive for vimentin, leading to the diagnosis of ES. With a diagnosis of ES, the treatment widely accepted is a comprehensive multidisciplinary approach of surgery, chemotherapy and radiotheraphy. [1]For this specific case, the patient underwent surgical removal of the tumor and is currently undergoing chemotherapy. However there was no plan for radiotheraphy. ES is thus a rare disease which may present similarly to other intracranial masses. Correlation between the cinical, radiologic and histopathologic findings, including tissue immunochemical analysis, is a crucial to its diagnosis. There are treatment options available today for this malignancy, but we must be prudent in weighing the pros and consto determine the best approach for the patient.
521 ## - TARGET AUDIENCE NOTE
Target audience note Research
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Research
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type Public note
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Research 08/04/2017   RAD20160006 R000513 08/04/2017 08/04/2017 Research ND