MARC details
000 -LEADER |
fixed length control field |
03050nam a22002537a 4500 |
001 - CONTROL NUMBER |
control field |
MED 2020 0013 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
PILC |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240720153215.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
211022b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Language of cataloging |
eng |
Transcribing agency |
FEU-NRMF MEDICAL LIBRARY |
Description conventions |
rda |
041 ## - LANGUAGE CODE |
Language code of text/sound track or separate title |
english |
050 ## - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
MED 2020 0013 |
245 ## - TITLE STATEMENT |
Title |
A Rare case of macrophage activation syndrome as initial presentation of systemic lupus erythematosus treated successfully using 2004 HLH treatment protocol / |
Statement of responsibility, etc. |
Kayla Pamela B. de la Cerna. |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
Place of publication, distribution, etc. |
Fairview, Quezon City: |
Name of publisher, distributor, etc. |
Department of Internal Medicine, FEU-NRMF, |
Date of publication, distribution, etc. |
2020. |
300 ## - PHYSICAL DESCRIPTION |
Other physical details |
tables; |
Dimensions |
(in folder) |
Accompanying material |
with flash drive (soft copy) |
336 ## - CONTENT TYPE |
Source |
rdacontent |
Content type term |
text |
337 ## - MEDIA TYPE |
Source |
rdamedia |
Media type term |
unmediated |
338 ## - CARRIER TYPE |
Source |
rdacarrier |
Carrier type term |
volume |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc |
Includes appendices and bibliographical references. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Abstract: This is a case of a 22 year old male diagnosed with systemic lupus in 2016 whose clinical presentation also fulfilled the criteria for macrophage activation syndrome. Two months prior to the diagnosis of SLE, he presented with thin scaly lesions with erythematous base on the scalp and hairline, followed by fever associated with headache and diplopia, then later developed partial memory loss. He was admitted and workup was done which revealed hepatosplenomegaly, multiple enlarged retroperitoneal and pelvic lymph nodes on CT scan, pancytopenia, hypertriglyceridemia, hyperferritinemia, meningitis with beginning hydrocephalus on cranial CT scan, positive ANA and anti-DsDNA and anticardiolipin. Bone marrow aspirate examination showed scattered histiocytes with hemophagocytic activity. While admitted, he developed epistaxis, disorientation, psychotic behaviors and seizures. Patient satisfied the SLICC criteria for SLE and the criteria for Macrophage Activation Syndrome. Patient was treated with 1 gram methylprednisolone pulse therapy once a day for 3 days, intrathecal methotrexate oral cyclosporine, and hydroxychloroquine. This was followed by using the 2004 treatment protocol for Hemophagocytic Lymphohistiocytosis which included intravenous etoposide, and high dose dexamethasone. The patient was discharged improved after 1 month. HLH treatment protocol was continued and was completed on an outpatient basis. Except for the avascular necrosis of the bilateral hips that developed 2 years after the treatment, no serious infection developed while the patient was on HLH treatment protocol. Throughout the 4 years, 3 episodes of lupus flare (rash, seizures, psychosis) were observed every time tapering of prednisone to less the 10mg once a day was attempted. Treatment for Rituximab was contemplated however, there was no consent given for Rituximab yet. Current maintenance medications of the patient are oral cyclosporin, prednisone 10 mg per day, hydroxychloroquine, aspirin, vitamin D, levetiracetam, olanzapine. No signs of lupus activity was noted during July 2020 check up. |
521 ## - TARGET AUDIENCE NOTE |
Target audience note |
Research - Department of Medicine |
700 ## - ADDED ENTRY--PERSONAL NAME |
Personal name |
de la Cerna, Kayla Pamela B., MD. |
Relator term |
author |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Library of Congress Classification |
Koha item type |
Room Use |