MARC details
| 000 -LEADER |
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| fixed length control field |
03907nam a22003137a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
MT 2022 0021 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
PILC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240720153241.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220407b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Language of cataloging |
eng |
| Transcribing agency |
FEU-NRMF MEDICAL LIBRARY |
| Description conventions |
rda |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
english |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
MT 2022 0021 |
| 245 ## - TITLE STATEMENT |
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| Title |
Diagnostic accuracy of TB-LAMP and GeneXpert MTB/RIF in detecting mycobacterium tuberculosis in sputum samples : |
| Remainder of title |
a systematic review / |
| Statement of responsibility, etc. |
Sherwin N. Benoza, Joever John C. Burigsay, Matt Gabriel A. Ines, Chris Mackenzie P. Pamplona, Clarisse Mariel m. Planton; Adlene Anne Atienza. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc. |
Fairview, Quezon City: |
| Name of publisher, distributor, etc. |
School of Medical Technology, FEU-NRMF, |
| Date of publication, distribution, etc. |
2022. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
104 pages: |
| Other physical details |
illustrations, tables; |
| Dimensions |
28 cm. |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
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| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
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| Source |
rdacarrier |
| Carrier type term |
volume |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes appendices and bibliographical references. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Abstract: Tuberculosis, which posed a great challenge to eradicate, caused thousands of deaths worldwide. Early diagnosis is essential for prompt management and treatment of the disease. Several TB diagnostic tools have already been established. However, there's still a need for a diagnostic tool with high diagnostic accuracy yet gives a rapid result at a reasonable cost. It aimed to assess the differences between GeneXpert MTB/RIF assay and TB-LAMP in comparison to conventional culture in terms of their sensitivity, turnaround time, and cost for the detection of Mycobacterium Tuberculosis in the sputum samples of patients suspected of having pulmonary tuberculosis. This study is a systematic review of the diagnostic accuracy of the tests GeneXpert MTB/RIF assay and TB-LAMP in comparison with conventional culture. PRISMA-DATA guidelines were utilized in this study. The studies that were included in this paper include those which studied patients suspected to having pulmonary tuberculosis, evaluated any of the index tests, used conventional culture as the reference standard and sputum samples as specimen, used observational or systematic review and meta-analysis, and studies from countries in which pulmonary tuberculosis is prevalent. In contrast, the study excluded studies that contain abstract only, published in other languages and with publication dates before January 2016. The electronic databases that were used for searching are Google Scholar, EBSCOhost, PubMed, ClinicalKey and ProQuest. The risk of bias and applicability was assessed using the QUADAS-2 tool. The study included 50 studies that were either observational and systematic review in nature. The total participants of the studies included is 21,308, which varied from pediatrics to geriatrics. The reference standard used by all the studies included in conventional culture The study results showed that the sensitivity and specificity of GeneXpert MTB/RIF assay ranges from 53.00% to 100.00% and 57.10% to 100.00%, respectively. On the other hand, the sensitivity and specificity of TB-LAMP ranges from 45.50% to 100.00% and 54.60% to 100.00%, respectively. In addition, conventional culture takes 15-21 days or more, and 1 hour to 3 hours for TB-LAMP and GeneXpert MTB/RIF before a result can be reported. Furthermore, the conventional culture could cost as high as US$ 70.29, the GeneXpert MTB/RIF assay costs US$12.69 and TB-LAMP cost US $9.40. The GeneXpert MTB/RIF assay is more expensive and specific than TB-LAMP. However, TB-LAMP is less expensive than GeneXpert MTB/RIF assay. Moreover, their turnaround time is almost similar to each other. |
| 521 ## - TARGET AUDIENCE NOTE |
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| Target audience note |
Thesis - School of Medical Technology |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Benoza, Sherwin N. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Burigsay, Joever John C. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ines, Matt Gabriel A. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Pamplona, Chris Mackenzie P. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Planton, Clarisse Mariel M. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Atienza, Adlene Anne, RMT |
| Relator term |
adviser |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Room Use |
