A Comparative study on the effect of micronized progesterone and oral dydrogesterone in the treatment of threatened abortion in a tertiary medical center from 2015 to 2019 / (Record no. 12284)

MARC details
000 -LEADER
fixed length control field 03116nam a22003137a 4500
001 - CONTROL NUMBER
control field OB 2021 0002
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720153244.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220427b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Language of cataloging eng
Transcribing agency FEU-NRMF MEDICAL LIBRARY
Description conventions rda
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title english
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number OB 2021 0002
245 ## - TITLE STATEMENT
Title A Comparative study on the effect of micronized progesterone and oral dydrogesterone in the treatment of threatened abortion in a tertiary medical center from 2015 to 2019 /
Statement of responsibility, etc. Denise Elaine A. Reyes; Lylah Reyes; Elizabeth Ahyong-Reyes.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Fairview, Quezon City:
Name of publisher, distributor, etc. Department of Obstetrics and Gynecology, FEU-NRMF,
Date of publication, distribution, etc. 2021.
300 ## - PHYSICAL DESCRIPTION
Extent 40 pages:
Other physical details illustrations, tables;
Dimensions (in folder) +
Accompanying material with flash drive (soft copy).
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes appendices and bibliographical references.
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: Threatened abortion occurs in 15% of pregnancies. If not prevented this may lead to pregnancy loss in 20% of cases. But with its resolution, it may lead to a better pregnancy outcome. Progesterone plays a key role in the prevention and management of threated abortion. To determine whether vaginal micronized progesterone is comparable with oral dydrogesterone in the treatment of Threatened abortion. This is a retrospective cohort study involving 573 charts of pregnant patients with threatened abortion who were either given oral dydrogesterone or vaginal micronized progesterone as treatment. Both out- and in-patient charts were reviewed and data extracted by the primary investigator. Baseline maternal characteristics gathered were compared between the two arms. The resolution of symptoms, duration of treatment, occurrence of adverse effects and pregnancy outcome were compared and analyzed between the type of progesterone using chi square and t-test. The resolution of signs and/or symptoms for patients with threatened abortion was not significantly different between those given vaginal micronized progesterone versus those who took oral dydrogesterone (p=0.401). The length of treatment ranged from 7 to 14 days to achieve resolution of signs and/or symptoms. A significantly higher proportion of cases in the oral dydrogesterone arm had nausea and somnolence, while increased vaginal discharge was noted in the vaginal progesterone group (p=0.001). The use of vaginal micronized progesterone and oral dydrogesterone achieved resolution of signs and/or symptoms of threatened abortion generally within 7 days but can be extended for 14 days. Systemic adverse effects of nausea and somnolence were more common in oral dydrogesterone. With micronized progesterone, because of its route of administration, vaginal discharge was more often observed.
521 ## - TARGET AUDIENCE NOTE
Target audience note Research - Department of Obstetrics & Gynecology
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element threatened abortion
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element dydrogesterone
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element micronized progesterone
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Reyes, Denise Elaine A., MD.
Relator term principal investigator
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Reyes, Lylah D., MD.
Relator term co-author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ahyong-Reyes, Elizabeth, MD.
Relator term co-author
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Room Use
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type Public note
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Research 04/27/2022   OB 2021 0002 R000839 04/27/2022 04/27/2022 Room Use with flash drive (soft copy)