A Randomized controlled trial comparing the efficacy of a seven day regimen of co-amoxiclav versus a single dose second generation cephalosporin (cefoxitin) as prophylactic antibiotic therapy for third and fourth degree perineal lacerations among post-partum patients in a tertiary medical center / (Record no. 12287)

MARC details
000 -LEADER
fixed length control field 03419nam a22003497a 4500
001 - CONTROL NUMBER
control field OB 2021 0005
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720153244.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220428b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Language of cataloging eng
Transcribing agency FEU-NRMF MEDICAL LIBRARY
Description conventions rda
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title english
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number OB 2021 0005
245 ## - TITLE STATEMENT
Title A Randomized controlled trial comparing the efficacy of a seven day regimen of co-amoxiclav versus a single dose second generation cephalosporin (cefoxitin) as prophylactic antibiotic therapy for third and fourth degree perineal lacerations among post-partum patients in a tertiary medical center /
Statement of responsibility, etc. Samantha Quennie Wanasen-Razon; Lylah D. Reyes; Jennifer Co.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Fairview, Quezon City:
Name of publisher, distributor, etc. Department of Obstetrics and Gynecology, FEU-NRMF,
Date of publication, distribution, etc. 2021.
300 ## - PHYSICAL DESCRIPTION
Extent 46 pages:
Other physical details illustrations, tables;
Dimensions (in folder) +
Accompanying material with flash drive (soft copy).
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes appendices and bibliographical references.
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: Episiotomy is a common obstetrical practice in the Philippines. However, particularly from midline episiotomy, a third- or fourth degree extension may not be prevented. This predisposes the episiotomy site to infection and wound breakdown due to bacterial contamination from the rectum. Compare the efficacy of single dose cefoxitin versus seven-day regimen of Co-amoxiclav in preventing wound infection of third- or fourth degree perineal tears among women who had episiotomy during vaginal delivery. Included were 64 women, 18 to 35 years old, who delivered vaginally and sustained a third or fourth degree laceration during episiotomy. Participants were randomly allocated to group A: single dose of Cefoxitin, 1 gram intravenous, given 30 minutes after delivery and group B: Co-amoxiclav, 750 mg twice a day for seven days postdelivery. Assessment for wound infection, pain/discomfort and adverse event rates as well as mean pain, REEDA scores and length of hospital stay between two groups were done right after episiorrphy, on the day of discharge and seven days after discharge. Wound infection, pain and discomfort were not noted for both treatment arms during the seven-day follow up period. The mean pain and REEDA scores tend to be higher among the participants in the co-amoxiclav group. There was also more adverse effects, such as nausea, dizziness and vomiting noted among those participants in the co-amoxiclav than in the cefoxitin group. Length of hospital stay ranged from 2 to 4 days with a mean of 2.98. Although, no statistically significant differences were noted between the two groups. Seven-day oral co-amoxiclav is comparable with single dose intravenous cefoxitin in preventing wound infection from third- or fourth degree perineal tears as well as safety. Thereby, compared to oral co-amoxiclav regimen, single dose cefoxitin is the cost-beneficial option among women with episiotomies having extension.
521 ## - TARGET AUDIENCE NOTE
Target audience note Research - Department of Obstetrics & Gynecology
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element cefoxitin
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element co-amoxiclav
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element episiotomy
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element third forth degree perineal laceration
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element anal sphincter injury
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element wound dehiscence
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Wanasen-Razon, Samantha Quennie, MD.
Relator term principal investigator
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Reyes, Lylah D., MD.
Relator term co-author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Co, Jennifer, MD.
Relator term co-author
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Room Use
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type Public note
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Research 04/28/2022   OB 2021 0005 R000876 04/28/2022 04/28/2022 Room Use with flash drive (soft copy)