MARC details
| 000 -LEADER |
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| fixed length control field |
03142nam a22002777a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
OPH 2022 0002 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
PILC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240720153319.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230621b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Language of cataloging |
eng |
| Transcribing agency |
FEU-NRMF MEDICAL LIBRARY |
| Description conventions |
rda |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
english |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
OPH 2022 0002 |
| 245 ## - TITLE STATEMENT |
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| Title |
Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy : |
| Remainder of title |
a systematic review and meta-analysis / |
| Statement of responsibility, etc. |
Jose Gabriel Recio, Rudolf Christian Palma and Manolito Reyes. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Fairview, Quezon City: |
| Name of publisher, distributor, etc. |
Department of Ophthalmology, FEU-NRMF, |
| Date of publication, distribution, etc. |
2022. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
25 pages: |
| Other physical details |
illustration, tables; |
| Dimensions |
(in folder) |
| Accompanying material |
with flash drive (soft copy). |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes appendices and bibliographical references. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Abstract: To determine the efficacy and safety of subconjunctival injection versus sponge-applied mitomycin C during trabeculectomy Systematic review and meta-analysis Data from 7 randomized controlled trials and case series studies We searched PubMed, The Cochrane Library, and Google scholar for studies that compared subconjunctival injection of Mitomycin-C (MMC) vs sponge-soaked application method, published up to June 30, 2022. NHLBI Quality Assessment Tools were used to evaluate the included studies. Mean difference for the 1-month postoperative IOP, 6-month postoperative IOP, 12-month postoperative IOP, final mean IOP reduction, bleb height, extent and vascularization and endothelial cell count changes, Odds ratio for the complications. Outcome measures were reported with a 95% confidence interval (CI), and P < 0.05 was considered statistically significant. Analysis was performed using Microsoft Excel and Review Manager software. Risk of bias of the studies showed low to moderate risk. In random effects model, the pooled mean difference showed: 1-month post op IOP -0.86 (95% CI: [-1.84, 0.11], P 0.08)., 6-month post op IOP 0.81 (95% CI: [-1.75, 0.14], P 0.10, 12-month post op IOP -0.04 (95% CI: [-1.61, 1.53], P 0.96, and final mean IOP -1.16 (95% CI: [-3.89, 1.56], P 0.40). Mean difference of bleb morphology revealed: height -0.35 (95% CI: [-0.50, -0.20], P <0.00001), extent 0.29 (95% CI: [0.17, 0.41], P <0.00001), and vascularization -0.47 (95% CI: [-0.65, -0.28], P <0.00001). Post-operative endothelial cell count showed -28.25 (95% CI: [-128.20, 71.70], P <0.58). Odds ratio of complications was -28.25 [-128.20, 71.70]. There were no significant difference in the mean IOP after 1,6 and12 months and mean IOP reduction of the intraoperative injection method and sponge soaked MMC. Blebs after sub tenon injection of MMC tended to be lower, more diffused and less vascularized. Endothelial cell count changes and complications in both methods were also comparable. Intraoperative injection of MMC is as effective as conventional sponge application. |
| 521 ## - TARGET AUDIENCE NOTE |
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| Target audience note |
Research - Department of Ophthalmology |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Recio, Jose Gabriel, MD. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Palma, Rudolf Christian, MD. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Reyes, Manolito, MD. |
| Relator term |
author |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Room Use |
