The role of high sensitivity c-reactive protein as a predictor of clinical outcome among admitted adult covid-19 patients. / (Record no. 12979)

MARC details
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fixed length control field 02947nam a22002777a 4500
001 - CONTROL NUMBER
control field R000736
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240806150243.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240806b |||||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Language of cataloging eng
Transcribing agency FEU-NRMF MEDICAL LIBRARY
Modifying agency rda
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number PATH 2023 0001
245 ## - TITLE STATEMENT
Title The role of high sensitivity c-reactive protein as a predictor of clinical outcome among admitted adult covid-19 patients. /
Remainder of title [Author]: Pereira, Jan Paulo S., Atibagos, Jr., Florido A., Esguerra, Mari Karr A.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Fairview, Quezon City:
Name of publisher, distributor, etc. Department of Pathology, FEU-NRMF,
Date of publication, distribution, etc. 2023
300 ## - PHYSICAL DESCRIPTION
Dimensions ( in folder )
Accompanying material with flash drive (soft copy)
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
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Source rdacarrier
Carrier type term volume
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references.
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT:<br/>Background: Elevated levels of interleukin-6 (IL-6) and the presence of cytokine storm is associated with a poorer outcome in COVID-19. IL-6 is the primary cytokine involved in the production of c-reactive protein (CRP) which is uniformly increased in cytokine storm. CRP also shows correlation with the severity of COVID-19 making it a promising predictor of clinical outcomes. It can be measured using monoclonal antibody-based test referred to as high sensitivity C-reactive protein (HS-CRP). This method has superior assay precision and accuracy in comparison to conventional means of CRP measurement. Objectives: To determine the role of HS-CRP as a predictor of clinical outcomes among admitted adult COVID-19 patients. Subjects and Methods: This is a retrospective cohort study. Randomly selected medical records of 110 adult COVID-19 patients who were admitted in a tertiary hospital were used. HS-CRP measurement was used as a predictor of outcomes which were divided into goad outcome (improvement and recovery) and poor outcome (deterioration and death).<br/>Results: Of the 110 patients, 62 were males while 48 were females. The age ranges from 22 to 95 years old with a median age of 60 years old. Among these patients, 85 were discharged while 25 died. As for the HS-CRP measurement, patients with > 20 final HS-CRP are 7.667 times more likely to expire compared to patients with < 20 final HS-CRP. It was observed that for every 1.0 unit increase in patients first HS-CRP, the odds of mortality also increase by 0.81%. there will also be a 1.21% increase in the odds of mortality for every 1.0 unit increase in patients final HS-CRP.<br/>Conclusion: Our study supports that an HS-CRP value-20.00 mg/L be used a predictor of poor outcome, particularly death. <br/>Keywords: COVIS-19, demographics, high sensitivity C-reactive protein, COVID-19 predictor of outcome, retrospective cohort study.<br/><br/><br/><br/>
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pathology & Laboratory Diagnosis
-- Research - Department of Pathology & Laboratory Diagnosis
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Personal name Pereira, Jan Paulo S.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Atibagos, Jr., Florido A.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Esguerra, Mari Karr A.
Relator term author
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Room Use
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation 08/06/2024   PATH 2023 0001 R000736 08/06/2024 08/06/2024 Room Use