Efficacy of lycopene from solanum Lycopersicum (TOMATO) as anticoagulant for prothrombin time and partial thromboplastin time, (Record no. 13160)

MARC details
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fixed length control field 04298nam a22003737a 4500
001 - CONTROL NUMBER
control field T002871
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20241029134456.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 241029b |||||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Language of cataloging eng
Transcribing agency FEU-NRMF MEDICAL LIBRARY
Modifying agency rda
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number MT 2024 0022 c.1
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Ancheta, Rajiv Jan M.,
Relator term author
245 01 - TITLE STATEMENT
Title Efficacy of lycopene from solanum Lycopersicum (TOMATO) as anticoagulant for prothrombin time and partial thromboplastin time,
Remainder of title [author]: Ancheta, Rajiv Jan M., Chua, Shannen Leigh J., De Leon, Moses Kelsey, Dilag, Jens Holly M., Estalani, Moira Erish V., Jasmin, Johnna Grace S., Macatangay, Mary Christlyn Joy A., Marasigan, Gillian S., Ong, David Raphael S.,Peralta, Ivan Moiz A.,Ramones, Haywee Angelie Ericka C.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Quezon City, Philippines;
Name of publisher, distributor, etc. FEU-NRMF Dr. Nicanor Reyes Medical Foundation Institute of Medicine,
Date of publication, distribution, etc. 2024
300 ## - PHYSICAL DESCRIPTION
Extent 130pages
Dimensions 28cm
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes Appendix
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT:<br/>Clinicians frequency order coagulation tests, such as prothrombin time (PT) and activated partial thromboplastic time ( aPTT), to assess blood clotting function in patients. Sodium citrate is widely used in medicine as an in-vitro anticoagulant, often utilized in coagulation studies. However, the DFA had highlighted concerns regarding supply chain problems related to a shortage of blood collection tubes, particularly sodium citrate tubes. This situation poses challenges for healthcare and laboratory workers, with some laboratories in the Philippines lacking readily available sodium citrate tubes. Moreover, Lycopene is an organic pigment classified as a carotenoid and is responsible for the red coloration of various fruits and vegetables. As reported by Hsiao et al. (2005), lycopene possesses anticoagulant properties. Among all processed product and raw varieties, tomatoes have the highest lycopene content, which could be used as a potential anticoagulant. To address the unavailability of these tubes, the researchers assessed the efficacy of commercially prepared lycopene extracted from tomatoes as another anticoagulation option for coagulation test such as PT and aPTT. Using a true experimental research method, this study involves three (3) phases: First, the authentication of the commercially prepared lycopene powder through physical and chemical tests. Second was the preparation of different lycopene powder concentrations (8 umol/L, 10 umol/ L, and 12 umol/L). third were the coagulation tests of PT and aPTT using lycopene as an anticoagulant. In the initial phase of the experiment, the researchers confirmed the purity and legitimacy of the commercially prepared lycopene, for the following phase, it was observed that 10 umol/L is the ideal concentration for lycopene because it showed maximum antiplatelet activity. However, in the third phase, a significant portion of the PT and aPTT results deviated from the reference range, rendering the findings unreliable. Results of the Yumizen G800 Hemostasis Analyzer predominantly yielded invalid PT and aPTT results, primarily attributable to procedural non-measurement errors. This study recommends broadening the scope of research to encompass other lycopene-rich fruits such as guava and winter melon and explore alternative coagulation machines, thereby providing insights into alternative sources with comparable or heightened anticoagulant effects.<br/>Keywords: sodium citrate, lycopene, solanum lycopersicum, alternative anticoagulant, coagulation test.<br/>
521 ## - TARGET AUDIENCE NOTE
Target audience note School of Medical Technology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Chua, Shannen Leigh J.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name De Leon, Moses Kelsey
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dilag, Jens Holly M.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Estalani, Moira Erish V.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Jasmin, Johnna Grace S
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Macatangay, Mary Christlyn Joy A.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Marasigan, Gillian S.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ong, David Raphael S.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Peralta, Ivan Moiz A.,
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ramones, Haywee Angelie Ericka C.
Relator term author
856 ## - ELECTRONIC LOCATION AND ACCESS
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation 10/29/2024   MT 2024 0022 c.1 T002871 10/29/2024 10/29/2024 Theses
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation 10/29/2024   MT 2024 0022 c.2 T002872 10/29/2024 10/29/2024 Theses
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation 10/29/2024   MT 2024 0022 c.3 T002873 10/29/2024 10/29/2024 Theses