MARC details
| 000 -LEADER |
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| fixed length control field |
02593nam a22003017a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
OPH 2010 0003 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
PILC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240720152605.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
160505b2010 xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Language of cataloging |
eng |
| Transcribing agency |
FEU-NRMF MEDICAL LIBRARY |
| Description conventions |
rda |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
english |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
OPH 2010 0003 |
| 245 ## - TITLE STATEMENT |
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| Title |
Prevalence of toxic optic neuropathy among patients on ethambutol treatment in a tertiary hospital / |
| Statement of responsibility, etc. |
Sarah R. Dimagiba and Pablo L. Rivadillo. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Fairview, Quezon City: |
| Name of publisher, distributor, etc. |
Department of Ophthalomogy, FEU-NRMF, |
| Date of publication, distribution, etc. |
2010. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Other physical details |
illustrations; |
| Dimensions |
(in folder) |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
volume |
| Source |
rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes appendices and bibliographical references. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Abstract: To determine the prevalence of Toxic Optic Neuropathy among patients on ethambutol treatment in a tertiary hospital. Patients diagnosed with pulmonary tuberculosis at FEU-NRMF Medical Center from January 2009 - April 2010 was referred to Ophthalmology service for baseline distance visual acuity testing, color vision testing and fundus examination prior to the intake of anti-tuberculosis drug which includes ethambutol. Patients were advised to follow up at 2 months, 4 months and 6 months during their treatment, dosage of the drug, co-morbidities such as Diabetes Mellitus and Hypertension as well as ophthalmic parameters were entered into standardized data-collection form, statistically analyzed, and compared. This study included 113 patients diagnosed with pulmonary tuberculosis, eight of which manifested signs of ethambutol toxicity. Results showed that there was a significant association between duration of treatment, dosage of ethambutol and comorbidities specifically Diabetes and Hypertension with ethambutol toxicity, and the most common ophthalmic parameter affected is color vision, which gradually decreased. Ethambutol-associated optic neuropathy is an established "ocular" drug complication. Giving the therapeutic dose does not guarantee that the patients will not develop ocular toxicity. Duration of the manifestations greatly vary with the health and the condition of the patient. Associated co-morbidities and old age can hasten the toxic effects of the drug which can eventually lead to detrimental ocular complications. |
| 521 ## - TARGET AUDIENCE NOTE |
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| Target audience note |
Research - Department of Ophthalmology |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
ethambutol toxic optic neuropathy |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
ophthalmic parameters |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
tuberculosis |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Dimagiba, Sarah R., MD. |
| Relator term |
author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Rivadillo, Pablo L., MD. |
| Relator term |
co-author |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Room Use |
