A Comparative study on the stability of liposomes from chicken egg yolk's phospholipid to that of commercially prepared phospholipid treated with d-tocopherol / (Record no. 7988)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02411nam a22002657a 4500 |
| 001 - CONTROL NUMBER | |
| control field | M BIO 1999 0003 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | PILC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240720152608.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160505b1999 xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Language of cataloging | eng |
| Transcribing agency | FEU-NRMF MEDICAL LIBRARY |
| Description conventions | rda |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | english |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | M BIO 1999 0003 |
| 245 ## - TITLE STATEMENT | |
| Title | A Comparative study on the stability of liposomes from chicken egg yolk's phospholipid to that of commercially prepared phospholipid treated with d-tocopherol / |
| Statement of responsibility, etc. | 1 Section A2; Michael Paul Tan. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Manila: |
| Name of publisher, distributor, etc. | Department of Biochemistry, FEU-NRMF, |
| Date of publication, distribution, etc. | 1999. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 37 pages: |
| Other physical details | illustration, tables; |
| Dimensions | 28 cm. |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| Content type term | text |
| 337 ## - MEDIA TYPE | |
| Source | rdamedia |
| Media type term | unmediated |
| 338 ## - CARRIER TYPE | |
| Source | rdacarrier |
| Carrier type term | volume |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes appendices and bibliographical references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract: Liposomes are effective vehicles in carrying therapeutic drugs and agents. The effectiveness of this active agent delivery system is largerly dependent on the stability of the liposomes` bilipid membrane. The stability is strengthen by the anti-oxidizing property of Vitamin E (D-tocopherol). Vitamin E acts as a scavenger of free radicals protecting the unsaturated bonds of the fatty acids in the bilipid membrane from destabilization by agents like hydrogen peroxide. D-tocopherol was applied to the bilipid membrane of liposomes formed from commercially purified phospholipids and to liposomes formed from phospholipids extracted from native chicken egg yolk. Fatty acid peroxidation was induced, and the percentage protection rendered by D-tocopherol was determined. A value of 63.02% protection for unsaturated fatty acid bonds in liposomes formed from commercially purified phospholipids was calculate, and a value of 33.33% protection for unsaturated fatty acids bonds in liposomes formed from phospholipid extracted from native chicken egg yolk was calculated. A comparison of the percentage protection of the unsaturated bonds of egg liposomes in the negative control and in the experiment is statistically significant (Z=3.17).A comparison of the percentage protection of the unsaturated bonds of liposomes formed from commercially purified phospholipids in the negative control and in the experience is statistically not significant (Z=1.68). |
| 521 ## - TARGET AUDIENCE NOTE | |
| Target audience note | Thesis - Department of Biochemistry & Nutrition |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | 1 Section A2 |
| Relator term | author |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tan, Michael Paul, MD. |
| Relator term | adviser |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | Room Use |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 02/11/2015 | M BIO 1999 0003 | T000452 | 02/15/2016 | 07/22/2016 | Room Use | |||||
| Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 11/22/2017 | M BIO 1999 0003 c.2 | T001763 | 11/22/2017 | 11/22/2017 | Room Use | |||||
| Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 11/22/2017 | M BIO 1999 0003 c.3 | T001765 | 11/22/2017 | 11/22/2017 | Room Use |
