MARC details
| 000 -LEADER |
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| fixed length control field |
03576nam a22003737a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
OB 2013 0006 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
PILC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240720152610.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
160505b2013 xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Language of cataloging |
eng |
| Transcribing agency |
FEU-NRMF MEDICAL LIBRARY |
| Description conventions |
rda |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
english |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
OB 2013 0006 |
| 245 ## - TITLE STATEMENT |
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| Title |
Efficacy of dequalinium vaginal suppository in the treatment of bacterial vaginosis compared with standard metronidazole oral regimen : |
| Remainder of title |
a randomized controlled trial / |
| Statement of responsibility, etc. |
Angela Eulalia Maling-Rugay, Romerico F. Torres and Lylah D. Reyes. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Fairview, Quezon City: |
| Name of publisher, distributor, etc. |
Department of Obstetrics and Gynecology, FEU-NRMF |
| Date of publication, distribution, etc. |
2013. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
45 pages: |
| Other physical details |
illustrations, tables; |
| Dimensions |
(in folder). |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
volume |
| Source |
rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes appendices and bibliographical references. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Abstract: The standard treatment for bacterial vaginosis is metronidazole. Side effects are not well tolerated by some patients and some develop resistance. Hence the search for treatment with less side effects and less resistance. To determine the efficacy of vaginal dequalinium chloride compared to oralmetronidazole in the treatment of bacterial vaginosis among non pregnant women. Fourty non-pregnant women and non-lactating women, 18-50 years old diagnosed with bacterial vaginosis by presence of vaginal discharge and malodor, Nugent's score of 4 and above, and clue cells seen in Gram stain, were randomly allocated to treatment groups. Group A received dequalinium chloride 10mg/vaginal tablet for 6 days at HS while Group B received metronidazole tablet, 500mg/tablet, 1 tablet per orem BID for 7 days. Microbiologic, clinical and complete cure rate as well as adverse effects of treatment were then assessed. Data entry and encoding was done using Epi info version 6. Analysis was done using stata version 9. Univariate analysis such as mean, median, mode and range were used to describe the characteristics of the subjects. Frequency distribution was used to describe the proportion of patients with microbiologic, clinical and complete cure. This was also used in describing proportion of the participants' acceptability in this study. Chi square will be used for comparison of dequalinum chloride and metronidazole between treatment-arms. Ninety five percent (19/20) of those in the dequalinium arm had gram-negative coccobacilli count of less than 10/hpf as compared to 80% (16/20) among those in the contol (p < 0.03). Lacbacilli was only restored among 25% of those in the metronidazole the and in 75% of the control group (p= 0.002). Reduced amount of discharge was observed in all participants in both two groups. Malodor of the discharge disappeared in 95% (19/20) of the H202 and 85% (17/20) of the control group (p=0.30). Dequalinium is comparable with the standard treatment. It is at par with the standard treatment in alleviating symptoms of bacterial vaginosis and reducing estimated coccobacilli. It is more effacious in restoring the normal flora. |
| 521 ## - TARGET AUDIENCE NOTE |
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| Target audience note |
Research - Department of Obstetrics & Gynecology |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
bacterial vaginosis |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
dequalinium chloride |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
metronidazole |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
gardnella vaginalis |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
provetella species |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
mycoplasma hominis |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
mobolincus |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
fusobacterium |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maling-Rugay, Angela Eulalia, MD. |
| Relator term |
principal investigator |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Torres, Romerico F., MD. |
| Relator term |
co-author |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Reyes, Lylah D., MD. |
| Relator term |
supervising investigator |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Room Use |
