Isolation of the hypouricemic components of methanolic leaf extract of persea americana mill in hyper-induced ICR mice / (Record no. 8660)
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000 -LEADER | |
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fixed length control field | 02283nam a22002897a 4500 |
001 - CONTROL NUMBER | |
control field | M BIO 2012 0006 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | PILC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20240720152651.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 160505b2012 xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE | |
Language of cataloging | eng |
Transcribing agency | FEU-NRMF MEDICAL LIBRARY |
Description conventions | rda |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | english |
050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
Classification number | M BIO 2012 0006 |
245 ## - TITLE STATEMENT | |
Title | Isolation of the hypouricemic components of methanolic leaf extract of persea americana mill in hyper-induced ICR mice / |
Statement of responsibility, etc. | Section C1; Joel L. Javate; Mari-Ann Bringas; Dolores Viliran. |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
Place of publication, distribution, etc. | Fairview, Quezon City: |
Name of publisher, distributor, etc. | Department of Biochemistry, FEU-NRMF, |
Date of publication, distribution, etc. | 2012. |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 86 pages: |
Other physical details | illustration, tables, photos; |
Dimensions | 28 cm. |
336 ## - CONTENT TYPE | |
Source | rdacontent |
Content type term | text |
337 ## - MEDIA TYPE | |
Source | rdamedia |
Media type term | unmediated |
338 ## - CARRIER TYPE | |
Source | rdacarrier |
Carrier type term | volume |
504 ## - BIBLIOGRAPHY, ETC. NOTE | |
Bibliography, etc | Includes appendices and bibliographical references. |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Abstract: This study investigated the hypouricemic effect of Persea Americana Mill (avocado) leaf extract (PAE) fraction on serum uric acid levels of ICR mice. Crude PAE was partitioned into hexane and ethyl acetate extracts and then subjected to vacuum column (VLC) chromatography to isolate the components present. Thin layer chromatography (TLC) was employed to check for fraction purity. The ICR mice were induced using potassium oxonate into a hyperuricemic state. Subsequently, the PAE fractions and controls were administered and blood was tested for uric acid levels. Nearly all of the PAE fractions had a hypouricemic effect: namely, one ethyl acetate fraction (70%H: 30%E) and two hexane fractions (60%H: 40%E and 20%H: 80%E) exhibited an even greater reduction in serum uric acid levels than Allopurinol, the gold standard pharmaceutical used for treatment of hyperuricemia. The fraction components were identified as flavonoid derivatives using infrared (IR) spectroscopy. However, a more specific determination of the flavonoids fell outside of the flavonoids fell outside of the limitations of this study. The data made available here obliges further into avocado extract as an alternative treatment for hyperuricemia |
521 ## - TARGET AUDIENCE NOTE | |
Target audience note | Thesis - Department of Biochemistry & Nutrition |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Section C1 |
Relator term | author |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Javate, Joel L., MD. |
Relator term | adviser |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Bringas, Mari-Ann, MD. |
Relator term | adviser |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Viliran, Dolores, MD. |
Relator term | adviser |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Library of Congress Classification |
Koha item type | Room Use |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 02/11/2015 | M BIO 2012 0006 | T000737 | 02/11/2015 | 07/22/2016 | Room Use |