Isolation of the hypouricemic components of methanolic leaf extract of persea americana mill in hyper-induced ICR mice / (Record no. 8660)

MARC details
000 -LEADER
fixed length control field 02283nam a22002897a 4500
001 - CONTROL NUMBER
control field M BIO 2012 0006
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152651.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b2012 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Language of cataloging eng
Transcribing agency FEU-NRMF MEDICAL LIBRARY
Description conventions rda
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title english
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number M BIO 2012 0006
245 ## - TITLE STATEMENT
Title Isolation of the hypouricemic components of methanolic leaf extract of persea americana mill in hyper-induced ICR mice /
Statement of responsibility, etc. Section C1; Joel L. Javate; Mari-Ann Bringas; Dolores Viliran.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Fairview, Quezon City:
Name of publisher, distributor, etc. Department of Biochemistry, FEU-NRMF,
Date of publication, distribution, etc. 2012.
300 ## - PHYSICAL DESCRIPTION
Extent 86 pages:
Other physical details illustration, tables, photos;
Dimensions 28 cm.
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes appendices and bibliographical references.
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: This study investigated the hypouricemic effect of Persea Americana Mill (avocado) leaf extract (PAE) fraction on serum uric acid levels of ICR mice. Crude PAE was partitioned into hexane and ethyl acetate extracts and then subjected to vacuum column (VLC) chromatography to isolate the components present. Thin layer chromatography (TLC) was employed to check for fraction purity. The ICR mice were induced using potassium oxonate into a hyperuricemic state. Subsequently, the PAE fractions and controls were administered and blood was tested for uric acid levels. Nearly all of the PAE fractions had a hypouricemic effect: namely, one ethyl acetate fraction (70%H: 30%E) and two hexane fractions (60%H: 40%E and 20%H: 80%E) exhibited an even greater reduction in serum uric acid levels than Allopurinol, the gold standard pharmaceutical used for treatment of hyperuricemia. The fraction components were identified as flavonoid derivatives using infrared (IR) spectroscopy. However, a more specific determination of the flavonoids fell outside of the flavonoids fell outside of the limitations of this study. The data made available here obliges further into avocado extract as an alternative treatment for hyperuricemia
521 ## - TARGET AUDIENCE NOTE
Target audience note Thesis - Department of Biochemistry & Nutrition
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Section C1
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Javate, Joel L., MD.
Relator term adviser
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Bringas, Mari-Ann, MD.
Relator term adviser
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Viliran, Dolores, MD.
Relator term adviser
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Room Use
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   M BIO 2012 0006 T000737 02/11/2015 07/22/2016 Room Use