A Study on the efficacy of alpha-N-acetylgalactosaminidase (naga) from clostridium perfringens in cleaving N-galactosamine from type a blood / (Record no. 8663)

MARC details
000 -LEADER
fixed length control field 02486nam a22002657a 4500
001 - CONTROL NUMBER
control field M BIO 2012 0009
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152651.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b2012 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Language of cataloging eng
Transcribing agency FEU-NRMF MEDICAL LIBRARY
Description conventions rda
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title english
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number M BIO 2012 0009
245 ## - TITLE STATEMENT
Title A Study on the efficacy of alpha-N-acetylgalactosaminidase (naga) from clostridium perfringens in cleaving N-galactosamine from type a blood /
Statement of responsibility, etc. Section D1; Anna Belen I. Alensuela.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Fairview, Quezon City:
Name of publisher, distributor, etc. Department of Biochemistry, FEU-NRMF,
Date of publication, distribution, etc. 2012.
300 ## - PHYSICAL DESCRIPTION
Extent 31 pages:
Other physical details illustration, tables, photos;
Dimensions 258 cm.
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes appendices and bibliographical references.
520 ## - SUMMARY, ETC.
Summary, etc. Abstract: Blood is an essential component of the human body. It serves a multitude of functions among which are oxygenation, waste product elimination, immunity and, most importantly, maintenance of homeostasis. Blood replacement or transfusion has been proven to be a highly effective therapy which saves lives of millions of people every day. Non-government organization (NGOs) and other globally-accredited organizations have acknowledged the fact that blood scarcity has been a problem both for the third world and developing countries alike. The study aimed to investigate a possible solution to this problem by extracting and isolating alpha-N-acetylgalactoseaminidase from the bacteria Clostridium perfringens. Partial isolation of C. perfringens was accomplished through gel-filtration chromatography using Sephadex G-100 column. Alpha-N-acetylgalactoseaminidase is known to convert type A to type O red cells. It cleaves the type A red cell`s immunodominant sugar leaving behind the L-fucose terminal end which makes the type A red cell similar to type O red cells. Two volunteers with blood types A and O participated in this study and 6ml of bloods are extracted. Three set-ups were used. Set-up A is the positive control, set-up B is the negative control and set-up C is the experimental control with type A blood and NAGA. The mixture of type A blood and enzyme solution was positive for agglutination when tested with anti-A serum. Hence, results were negative for the conversion of Type A into Type O blood.
521 ## - TARGET AUDIENCE NOTE
Target audience note Thesis - Department of Biochemistry & Nutrition
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Section D1
Relator term author
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Alensuela, Anna Belen I., MD.
Relator term professor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Room Use
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   M BIO 2012 0009 T000740 02/11/2015 07/22/2016 Room Use