MARC details
000 -LEADER |
fixed length control field |
02486nam a22002657a 4500 |
001 - CONTROL NUMBER |
control field |
M BIO 2012 0009 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
PILC |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240720152651.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
160505b2012 xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Language of cataloging |
eng |
Transcribing agency |
FEU-NRMF MEDICAL LIBRARY |
Description conventions |
rda |
041 ## - LANGUAGE CODE |
Language code of text/sound track or separate title |
english |
050 ## - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
M BIO 2012 0009 |
245 ## - TITLE STATEMENT |
Title |
A Study on the efficacy of alpha-N-acetylgalactosaminidase (naga) from clostridium perfringens in cleaving N-galactosamine from type a blood / |
Statement of responsibility, etc. |
Section D1; Anna Belen I. Alensuela. |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
Place of publication, distribution, etc. |
Fairview, Quezon City: |
Name of publisher, distributor, etc. |
Department of Biochemistry, FEU-NRMF, |
Date of publication, distribution, etc. |
2012. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
31 pages: |
Other physical details |
illustration, tables, photos; |
Dimensions |
258 cm. |
336 ## - CONTENT TYPE |
Source |
rdacontent |
Content type term |
text |
337 ## - MEDIA TYPE |
Source |
rdamedia |
Media type term |
unmediated |
338 ## - CARRIER TYPE |
Source |
rdacarrier |
Carrier type term |
volume |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc |
Includes appendices and bibliographical references. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Abstract: Blood is an essential component of the human body. It serves a multitude of functions among which are oxygenation, waste product elimination, immunity and, most importantly, maintenance of homeostasis. Blood replacement or transfusion has been proven to be a highly effective therapy which saves lives of millions of people every day. Non-government organization (NGOs) and other globally-accredited organizations have acknowledged the fact that blood scarcity has been a problem both for the third world and developing countries alike. The study aimed to investigate a possible solution to this problem by extracting and isolating alpha-N-acetylgalactoseaminidase from the bacteria Clostridium perfringens. Partial isolation of C. perfringens was accomplished through gel-filtration chromatography using Sephadex G-100 column. Alpha-N-acetylgalactoseaminidase is known to convert type A to type O red cells. It cleaves the type A red cell`s immunodominant sugar leaving behind the L-fucose terminal end which makes the type A red cell similar to type O red cells. Two volunteers with blood types A and O participated in this study and 6ml of bloods are extracted. Three set-ups were used. Set-up A is the positive control, set-up B is the negative control and set-up C is the experimental control with type A blood and NAGA. The mixture of type A blood and enzyme solution was positive for agglutination when tested with anti-A serum. Hence, results were negative for the conversion of Type A into Type O blood. |
521 ## - TARGET AUDIENCE NOTE |
Target audience note |
Thesis - Department of Biochemistry & Nutrition |
700 ## - ADDED ENTRY--PERSONAL NAME |
Personal name |
Section D1 |
Relator term |
author |
700 ## - ADDED ENTRY--PERSONAL NAME |
Personal name |
Alensuela, Anna Belen I., MD. |
Relator term |
professor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Library of Congress Classification |
Koha item type |
Room Use |