A COMPARATIVE STUDY OF GLIBENCLAMIDE (SUCRON) AND AMPALAYA CAPSULE (MOMORDICA CHARANTIA) IN LOWERING THE BLOOD GLUCOSE LEVEL IN GUINEA PIGS (Record no. 8908)

MARC details
000 -LEADER
fixed length control field 03202nam a22002777a 4500
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152725.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b xxu||||| |||| 00| 0 eng dND
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number MPHARND022
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Barangan, Shella Marie B.
245 ## - TITLE STATEMENT
Title A COMPARATIVE STUDY OF GLIBENCLAMIDE (SUCRON) AND AMPALAYA CAPSULE (MOMORDICA CHARANTIA) IN LOWERING THE BLOOD GLUCOSE LEVEL IN GUINEA PIGS
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice ND
Place of production, publication, distribution, manufacture QUEZON CITY
Name of producer, publisher, distributor, manufacturer FEU-NRMF
300 ## - PHYSICAL DESCRIPTION
Extent NO DATE
520 ## - SUMMARY, ETC.
Summary, etc. Diabetes Mellitus (DM) is the most important disease involving the endocrine pancreas. It is a chronic disorder of carbohydrate, fat and protein metabolism characterized by hyperglycemia. The blood glucose of a diabetic patient exceeds the normal which is 70-110 mg/dL. Fasting blood sugar of over 140 mg/dL in two consec utive examinations is diagnostic of Diabetes Mellitus. Type 1 diabetes is a severe form associated with ketoacidosis. It commonly occurs in the younger age group. In this case, the circulating insulin is virtually absent. Plasma glucagon is elevated and the pancreatic B-cells fail to respond to all insulinogenic stimuli. Exogenous insulin is therefore required to reverse the catabolic state, prevent ketosis and reduce hyperglucagonemia and the elevated blood glucose level. This experimental study focuses more on the oral hypoglycemic agent which is used in the treatment of Type II diabetes, also known as Non-insulin dependent diabetes mellitus. In this type, there is both insulin resistance and impaired regulation of insulin secretion. Treatment is initially and weight reduction but when these attempts to correct hyperglycemia fail, oral hypoglycemic agents are usually prescribed. There are several drugs available for the treatment of diabetes mellitus. This experiment is designed to compare the commercially available ampalaya capsule and one of the commonly used anti-diabetic drugs, which has been prescibed by physicians for decades in treating Type II diabetes. For a drug to be called the gold standard, it must be universally accepted. There are three classes of anti-diabetic drugs which work in different ways to lower blood sugar. Glibenclamide, called glyburide in the USA, may be the most prescribed anti-diabetic drug. Guinea pigs were given oral glucose powder to induce hyperglycemia prior to administration of the ampalaya capsule and glibenclamide. Both drugs caused a decrease on the blood sugar level. However, the ampalaya capsule showed a faster onset of action. Hence, the researchers conclude that ampalaya may be administered for acute attacks of hyperglycemia and may also be used as a maintenance drug. There has been no documented side effect of the drug since it came from an organic source.
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pharmacology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Almojera, Beverly
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Galino, Joy
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Leano, Grecyl
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Vallendo, Gilson
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Villapando, Jocelyn
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Pangan, Aileneli
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Taaca, Rochelle
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Comia, Jessie
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Date last checked out Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015 1 MPHARND0022 T000926 11/19/2018 11/19/2018 07/22/2016 Theses