EVALUATION OF THE ANALGESIC ACTIVITY OF MIMOSA PUDICA L (MAKAHIYA) EXTRACT ON FEMALE SWISS WEBSTER MICE (Record no. 8920)

MARC details
000 -LEADER
fixed length control field 02039nam a22002777a 4500
001 - CONTROL NUMBER
control field 5433
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152726.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b xxu||||| |||| 00| 0 eng dND
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number THE M-PHAR ND 0034
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Cadag, Edelweiss A.
245 ## - TITLE STATEMENT
Title EVALUATION OF THE ANALGESIC ACTIVITY OF MIMOSA PUDICA L (MAKAHIYA) EXTRACT ON FEMALE SWISS WEBSTER MICE
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice ND
336 ## - CONTENT TYPE
Content type term Text
337 ## - MEDIA TYPE
Media type term Unmediated
338 ## - CARRIER TYPE
Carrier type term Volume
502 ## - DISSERTATION NOTE
Degree type Pharmacology
Miscellaneous information Thesis
520 ## - SUMMARY, ETC.
Summary, etc. The efficacy of the analgesic effect of the Makahiya (Mimosa pudica) leaf extract was tested in female Swiss Webster mice. The decoction was prepared using a 1 : 1 ratio of distilled water and fresh Makahiya leaves. The mice were screened prior to experimentation. The lethal dose was detrmined using 2 trials: with a low dose of 0.02 mg/ml and a higher dose of 0.15 mg/ml. Different concentrations of the Makahiya extract were administered to 3 treatment groups (0.03, 0.06 and 1.0 mg/ml doses). Two pain stimulus were subjected to the mice: thermal (heat-plate method) and chemical (Acethycholine-induced writing method). Results were recorded in seconds. Three trials were done with a 3-day interval per trial. The results were analyzed using the t-test. In the heat plate method, only the 0.06 and 1.0 mg/ml concentrations of the decoction showed significant prolongation of the reaction time, with a t=2.68 and 1=2.86, respectively )t value of 1.33). In the Acetylcholine-induced abdominal writhing, the decoction was tested in comparison with paracetamol. All three concentrations showed no significant prolongation of reaction time of the test mice. This prompts for further recommendation of expanding the dose range to at least 5 doses within the effective dose range.
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pharmacology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Atienza, Girlie O.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Arcellana, Jasmin V.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Mercado, Maureen, S.P.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type Date last checked out
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHARND0034c.1 T000943 02/11/2015 07/22/2016 Theses  
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015 1 MPHARND0034c.2 T000944 01/17/2018 07/22/2016 Theses 01/17/2018