EVALUATION OF THE ANALGESIC ACTIVITY OF MIMOSA PUDICA L (MAKAHIYA) EXTRACT ON FEMALE SWISS WEBSTER MICE (Record no. 8920)
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fixed length control field | 02039nam a22002777a 4500 |
001 - CONTROL NUMBER | |
control field | 5433 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | PILC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20240720152726.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 160505b xxu||||| |||| 00| 0 eng dND |
040 ## - CATALOGING SOURCE | |
Transcribing agency | FEU-NRMF MEDICAL LIBRARY |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | English |
050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
Classification number | THE M-PHAR ND 0034 |
100 ## - MAIN ENTRY--PERSONAL NAME | |
Personal name | Cadag, Edelweiss A. |
245 ## - TITLE STATEMENT | |
Title | EVALUATION OF THE ANALGESIC ACTIVITY OF MIMOSA PUDICA L (MAKAHIYA) EXTRACT ON FEMALE SWISS WEBSTER MICE |
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
Date of production, publication, distribution, manufacture, or copyright notice | ND |
336 ## - CONTENT TYPE | |
Content type term | Text |
337 ## - MEDIA TYPE | |
Media type term | Unmediated |
338 ## - CARRIER TYPE | |
Carrier type term | Volume |
502 ## - DISSERTATION NOTE | |
Degree type | Pharmacology |
Miscellaneous information | Thesis |
520 ## - SUMMARY, ETC. | |
Summary, etc. | The efficacy of the analgesic effect of the Makahiya (Mimosa pudica) leaf extract was tested in female Swiss Webster mice. The decoction was prepared using a 1 : 1 ratio of distilled water and fresh Makahiya leaves. The mice were screened prior to experimentation. The lethal dose was detrmined using 2 trials: with a low dose of 0.02 mg/ml and a higher dose of 0.15 mg/ml. Different concentrations of the Makahiya extract were administered to 3 treatment groups (0.03, 0.06 and 1.0 mg/ml doses). Two pain stimulus were subjected to the mice: thermal (heat-plate method) and chemical (Acethycholine-induced writing method). Results were recorded in seconds. Three trials were done with a 3-day interval per trial. The results were analyzed using the t-test. In the heat plate method, only the 0.06 and 1.0 mg/ml concentrations of the decoction showed significant prolongation of the reaction time, with a t=2.68 and 1=2.86, respectively )t value of 1.33). In the Acetylcholine-induced abdominal writhing, the decoction was tested in comparison with paracetamol. All three concentrations showed no significant prolongation of reaction time of the test mice. This prompts for further recommendation of expanding the dose range to at least 5 doses within the effective dose range. |
521 ## - TARGET AUDIENCE NOTE | |
Target audience note | Department of Pharmacology |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Atienza, Girlie O. |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Arcellana, Jasmin V. |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mercado, Maureen, S.P. |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Library of Congress Classification |
Koha item type | Theses |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type | Date last checked out |
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Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 02/11/2015 | MPHARND0034c.1 | T000943 | 02/11/2015 | 07/22/2016 | Theses | ||||||
Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 02/11/2015 | 1 | MPHARND0034c.2 | T000944 | 01/17/2018 | 07/22/2016 | Theses | 01/17/2018 |