A COMPARATIVE STUDY ON THE EFFECT OF NORMAL AND MEGADOSES OF ASCORBIC ACID ON BLOOD CHOLESTEROL LEVEL OF GUINEA PIGS (Record no. 8936)

MARC details
000 -LEADER
fixed length control field 01889nam a22001817a 4500
001 - CONTROL NUMBER
control field 544
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152728.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b1999 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number MPHAR19990001
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Group 3 2C Medical Students
245 ## - TITLE STATEMENT
Title A COMPARATIVE STUDY ON THE EFFECT OF NORMAL AND MEGADOSES OF ASCORBIC ACID ON BLOOD CHOLESTEROL LEVEL OF GUINEA PIGS
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. QUEZON CITY
Name of publisher, distributor, etc. FEU-NRMF
Date of publication, distribution, etc. March 1999
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT: An extensive literature has accumulated concerning the effect of Vitamin C (ascorbic acid) on practically every function of the body. Its present popularity lies on its wide availability at a low cost. From this arise the concern about its controversial effect on cholesterol, rendering it a possible preventive measure in the development of cardiovascular disease. However, questions also arise from its probable side effects. To compare the effects of normal and megadoses of ascorbic acid on plasma cholesterol levels, 10 healthy guinea pigs underwent controlled and regulated diet, receiving 10ml water and 6g darak pellets/100g body weight. They were orally administered with 35, 1000, and 2000 mg Ascorbic acid. Each diet was used up for 5 days with a wash-out period in between. Plasma cholesterol was analyzed using fasting and 2-hour postprandial sample. It was found that 5-day administration of Ascorbic acid resulted in a significant decrease fasting and postprandial levels of cholesterol in normal (35 mg) dosage (by 1 and 0.23 mmol/L, respectively). Insignificant increase was, however, noted in fasting levels using 1000 and 2000 mg megadoses (by 0.07 and 0.03 mmol/L, respectively) and 1000mg postprandial dosage ( by 0.03 mmol/L). 2000 mg postprandial dosage showed no significant decrease (by 0.12 mmol/L).
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pharmacology
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHAR19990001C.1 T000758 02/11/2015 07/22/2016 Theses
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHAR19990001C.2 T000759 02/11/2015 07/22/2016 Theses