THE HYPOGLYCEMIC EFFECT OF 100% ONION (ALLIUM CEPA) BULB EXTRACT ON THE BLOOD GLUCOSE LEVEL OF THE GLUCOSE WATER INDUCED HYPERGLYCEMIC MALE ALBINO RATS (RATUS NORVEIGICUS) (Record no. 8962)
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fixed length control field | 03367nam a22003377a 4500 |
001 - CONTROL NUMBER | |
control field | 5475 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | PILC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20240720152730.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 160505b2001 xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE | |
Transcribing agency | FEU-NRMF MEDICAL LIBRARY |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | English |
050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
Classification number | THE M-PHAR 2001 0002 |
100 ## - MAIN ENTRY--PERSONAL NAME | |
Personal name | Merced, Razel |
245 ## - TITLE STATEMENT | |
Title | THE HYPOGLYCEMIC EFFECT OF 100% ONION (ALLIUM CEPA) BULB EXTRACT ON THE BLOOD GLUCOSE LEVEL OF THE GLUCOSE WATER INDUCED HYPERGLYCEMIC MALE ALBINO RATS (RATUS NORVEIGICUS) |
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
Date of production, publication, distribution, manufacture, or copyright notice | 2001 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | NO NO. OF PAGES |
336 ## - CONTENT TYPE | |
Content type term | Text |
337 ## - MEDIA TYPE | |
Media type term | Unmediated |
338 ## - CARRIER TYPE | |
Carrier type term | Volume |
502 ## - DISSERTATION NOTE | |
Degree type | Pharmacology |
Miscellaneous information | Thesis |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Diabetes has been one of the main diseases that gave problems to many populations in the world. The study was based on the idea of finding an accessible hypoglycemic agent that is within the natural flora of the country. Onion is a very promising natural resource,aside from being an herb, a favorite spice in food, and now as a medicinal plant. The study attempted to find the effect of glucose-water induced hyperglycemic male albino rats (Ratus norveigicus) by using 100% onion (Allium cepa) bulb extract,Glibenclamide (Euglucon) as positive control and distilled water as negative control. 30 male albino rats were used as subjects, were brought to Pharmacology Department Laboratory (FEU-NRMF) and were acclimatized for one week. Then the rats were fasted for 24 hours, glucose-water was given as food substitute, and left alone again for 24 hours. The blood glucose levels were determined for hyperglycemic levels for the 3 groups. Then the onion extract, Glibenclamide and distilled water were given. The rats were left to stay for 1 hour. The blood glucose was extracted thereafter for the succeeding two and three hours, with an hour interval. ANOVA (Analysis of Variance) was used with a confidence interval at 95%. The results showed an increase in the blood glucose levels for the first hour and a marked decrease in the second hour, as well as the third hour for the group that received the onion and a continued increase of blood glucose for the second and third hour on the rats that received Glibenclamide. The changes in the blood values of the rats that received distilled water were so minimal. The results of the study showed that onion probably could be used as a hypoglycemic agent, it`s effect is transient and delayed. However, further studies should be made utilizing an increased dosage of onion extract, longer duration of study, use of additional subjects or study groups, using other hypoglycemic agents, use of transgenic mice and the use of alloxan and streptozocin as hypoglycemic agents. |
521 ## - TARGET AUDIENCE NOTE | |
Target audience note | Department of Pharmacology |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Sollano, Christian |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Ciron, Jacqueline |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Relativo, Homer |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Reta, Sirius Marie |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Tayam, Gelaine |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Usita, Julius |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Yoshida, Alfonso Syoei |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Library of Congress Classification |
Koha item type | Theses |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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Library of Congress Classification | Far Eastern University - Nicanor Reyes Medical Foundation | Far Eastern University - Nicanor Reyes Medical Foundation | Theses | 02/11/2015 | MPHAR20010002 | T000773 | 02/11/2015 | 07/22/2016 | Theses |