A RESEARCH ON THE POTENTIATING EFFECTS OF SALICYLATES ON GLIBENCLAMIDE IN LOWERING BLOOD GLUCOSE LEVEL (Record no. 8968)

MARC details
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fixed length control field 02481nam a22003257a 4500
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control field 5481
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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152731.0
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fixed length control field 160505b2001 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
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Language code of text/sound track or separate title English
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Classification number THE M-PHAR 2001 0008
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Ong, Margie Lorraine O.
245 ## - TITLE STATEMENT
Title A RESEARCH ON THE POTENTIATING EFFECTS OF SALICYLATES ON GLIBENCLAMIDE IN LOWERING BLOOD GLUCOSE LEVEL
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 2001
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Content type term Text
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Media type term Unmediated
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Degree type Pharmacology
Miscellaneous information Thesis
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Summary, etc. A group of 10 albino rats weighing 200 to 250 gm procured at the Department of Science and Technology was used. They were fasted for 8 hours in preparation for the modified oral glucose tolerance test. After 8 hours of fasting each of them was taken their fasting blood glucose level via glucometer method and this would serve as their baseline level. After which, they were administered 10 % glucose solution ( 4 g/Kg BW ) orally to induce hyperglycemia and the rise of their glucose level was taken again into record by obtaining another blood glucose determination. Blood samples were taken again subsequently with an interval of 30 min. for a span of 120 min. After a 3 day interval, same ten rats was taken their fasting blood sugar after 8 hours fasting and was given 10% glucose solution to induced hyperglycemia. Blood samples were again collected to observe the rise in glucose level. They were given Glibenclamide (2.5mg/Kg BW), an oral hypoglycemic agent and the effect of lowering the blood glucose level is determined by blood collected every 30 min for 120 min. A 3-day interval was given to ensure a total wash out period for the drugs before the next procedure is done. The 10 rats were again induced to hyperglycemia but this were given Glibenclamide with salicylate (30 mg/kg BW) and observed for the results. The results were used to investigate the hypoglycemic effect of Glibenclamide with salicylates as to Glibenclamide when used alone. The results showed that the combination of the two drugs has greater degree of Hypoglycemic effect than Glibenclamide alone.
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pharmacology
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Personal name Pagud, Anna Liezle T.
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Personal name Protacio, Shiela M.
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Personal name Yi Heng, Ree
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Personal name Reyes, Marcelle B.
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Personal name Rosales, Maritoni L.
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Personal name Samonte, Precious Emary E.
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Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHAR20010008 T000782 02/11/2015 07/22/2016 Theses