THE ANTIMUTAGENIC EFFECT OF SWEET POTATO (IPOMOEA BATATAS) ON MITOMYCIN-C INDUCED MALE ALBINO RAT (Record no. 8981)

MARC details
000 -LEADER
fixed length control field 02889nam a22003377a 4500
001 - CONTROL NUMBER
control field 5494
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152732.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b2001 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number THE M-PHAR 2001 0021
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Bernardo, Bernadette
245 ## - TITLE STATEMENT
Title THE ANTIMUTAGENIC EFFECT OF SWEET POTATO (IPOMOEA BATATAS) ON MITOMYCIN-C INDUCED MALE ALBINO RAT
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 2001
336 ## - CONTENT TYPE
Content type term Text
337 ## - MEDIA TYPE
Media type term Unmediated
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Carrier type term Volume
502 ## - DISSERTATION NOTE
Degree type Pharmacology
Miscellaneous information Thesis
520 ## - SUMMARY, ETC.
Summary, etc. Cancer is one of the fatal diseases known to man. Economic status, culture, genetics and lifestyle are just some of the multifactorial contributors that come into play in the causation of the disease. Seeing the need for cheap and alternative or adjunct to current therapy, this study aims to demonstrate the antimutagenic effect of Ipomoea batatas (kamote) on Mitomycin-C-induced tats. In the experiment, 15 male albino rats were divided into 3 groups with 5 rats each After a week of acclimatization, Group 1 as the baseline negative was given NSS only, Group 2 was given Mitomycin-CC, and Group 3 was given Mitomycin-C and kamote extract After 3 days, the animals were sacrificed. The femurs were isolated and the bone marrow aspirated through syringe. The aspirate was smeared, air dried, stained, and then viewed under compound light microscope. The number of micronuclei was counted per 1,000 rbcs/slide as a measures of mutagenic effect. The values obtained were averaged and analyzed using Analysis of Variance (ANOVA) at F-distribution and Scheffe`s test with a confidence interval of 95%. The result showed that was a significant different between the three groups. There was a significant difference between the frequency of micronuclei in the rbc`s of the group of rats induced with Mitomycin-C and then given kamote extract than those of the group of rats from which kamote extract was witheld, with group 3 mice showing considerably less micronuclei. With the defined parameters for antimutagenicity, plus the demonstrated decrease in micronuclei count in group 3 rats, the researchers concluded the kamote extract as antimutagenic in Mitomycin-C-induced rats.
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pharmacology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Fababier, Richard
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ferry, Edgar Allen
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Personal name Galman, Lanie
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Personal name Ilo, Khristine
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Personal name Mong, Abigail
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Personal name Pablo, Haydee
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Personal name Santiago, Maribel
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Usita Julius
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHAR20010021c.1 T000897 02/11/2015 07/22/2016 Theses
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHAR20010021c.2 T000898 02/11/2015 07/22/2016 Theses