THE COMPARATIVE EFFECTS OF SUGARDINE AND TAWASDINE IN HEALING OF A PARTIAL THICKNESS BURN IN ALBINO MICE (MUS MUSCULUS) (Record no. 9006)

MARC details
000 -LEADER
fixed length control field 04224nam a22003257a 4500
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152734.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b2003 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title English
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number MPHAR20030011
245 ## - TITLE STATEMENT
Title THE COMPARATIVE EFFECTS OF SUGARDINE AND TAWASDINE IN HEALING OF A PARTIAL THICKNESS BURN IN ALBINO MICE (MUS MUSCULUS)
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Quezon City
Name of publisher, distributor, etc. FEU-NRMF
Date of publication, distribution, etc. March 2003
300 ## - PHYSICAL DESCRIPTION
Extent 24 pages
336 ## - CONTENT TYPE
Content type term Text
337 ## - MEDIA TYPE
Media type term Unmediated
338 ## - CARRIER TYPE
Carrier type term Volume
520 ## - SUMMARY, ETC.
Summary, etc. ABSTRACT: In spite of modern techniques in surgical intervention and discoveries of new antimicrobials wound healing and wound infection have been a problem since people nowadays look for an alternative antiseptic and anti-infective agents that have the same effect as the commercially prepared ones but assuring its availability and cost effectiveness. In this study, the objective of the researchers is to compare the effects of Sugardine and Tawadine in healing of a partial thickness burn in albino mice. The experiment aim to evaluate the wound healing properties of Sugardine (sugar in Betadine) and Tawasdine (tawas in Betadine) on artificially created partial thickness burn compared to commercially prepared agents such as Betadine for positive control and NSS for negative control. The study assessed wound healing properties specially on degree of epitheliazation, fibroblast proliferation, connective tissue deposition and neovascularization. A three-week study was done using a total of 84 Albino mice as subjects, with equal male and female population, same age between 8-10 weeks old, body weight between 21-23 grams and randomly divided into four groups (Groups 1,2,3,4). The male and female mice in each group were separated in order to prevent reproduction. At Day 0 partial thickness burn was made in the shaved dorsal aspect of the mice using a screw head with one centimeter diameter heated until red in an alcohol lamp. The first group which is the control group was treated with solution A (Betadine) at wound A and solution B (NSS) at wound B. Group 2,3,4 were the experimental groups treated with solution C (Sugardine) at wound C and solution D (Tawasdine) at wound D. Application of the solutions was done by a blinded individual. At Day 1, biopsy from each group was done and application of solutions. At Day 2- 21 continued biopsy from each group and application of solutions to remaining mice. Results were tabulated and analyzed comparing the Sugardine and Tawasdine with Betadine and NSS on partial thickness burn. Epithelialization was found to be better in both Sugardine and Tawasdine groups as compared to the control groups. Fibroblast proliferation and connective tissue deposition started earlier and achieved its maximal degree in both experimental groups and appeared to be better thant the Betadine. and NSS treated groups. With neovascularization, Sugardine showed greater number of capillaries at earlier day compared to Tawasdine. Based on the outcome it was concluded that Sugardine and Tawasdine have significant association in wound healing but Sugardine showed more significance on the parameters measured. The impressive results led the researchers to strongly recommend the use of these solutions in clinical management of wound healing. Further development and analysis of the findings will lead to better antiseptic and anti-infective agents in a lesser cost thus helping patients in a more practical way.
521 ## - TARGET AUDIENCE NOTE
Target audience note Department of Pharmacology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Abrenica, Norbert M.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dayro, Mary Jane S.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ilagan, Jasmin T.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Lorenzo, Jennifer Christy C.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Mendoza, Paraluman F.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Punongbayan, Rommel B.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Santos, Baby Belle A.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Sergio, Audrey Rose Felicity C.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Somintac, Kristine C.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015   MPHAR20030011 T000881 02/11/2015 07/22/2016 Theses
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/02/2018   MPHAR20030011c.2 T001793 02/02/2018 02/02/2018 Theses