ANTI-HYPERGLYCEMIC EFFECT OF ORIGANUM VULGARE (OREGANO) CRUDE LEAF EXTRACT WITH A COMPARATIVE STUDY ON ACARBOSE IN VIVO (Record no. 9021)

MARC details
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fixed length control field 03378nam a22004217a 4500
003 - CONTROL NUMBER IDENTIFIER
control field PILC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20240720152736.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 160505b2007 xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Transcribing agency FEU-NRMF MEDICAL LIBRARY
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number MPHAR20070001
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Personal name Section 2F
245 ## - TITLE STATEMENT
Title ANTI-HYPERGLYCEMIC EFFECT OF ORIGANUM VULGARE (OREGANO) CRUDE LEAF EXTRACT WITH A COMPARATIVE STUDY ON ACARBOSE IN VIVO
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. QUEZON CITY
Name of publisher, distributor, etc. FEU-NRMF
Date of publication, distribution, etc. 2007
300 ## - PHYSICAL DESCRIPTION
Extent 32 PAGES
520 ## - SUMMARY, ETC.
Summary, etc. Oregano vulgare (oregano) crude leaf extract using decoction extraction was compared to Acarbose in vivo, using 10% dextrose hyperglycemia-induced ICR mice. Hyperglycemic state of the test animals was achieved after the results of the mean value of after 10%dextrose oral administration showed significant increase in the serum blood glucose when compared to the levels of glucose in the blood before induction. 1-hour post prandial and 30-min post prandial glucose detrmination test, dubbed as trial I and trial 2 respectively were used to compare anti-hyperglycemic activity relative to time. Using one way-ANOVA test, the results showed a non significant difference of oregano and acarbose at trial 1 however, at trial 2, significant difference were noted. The results would reveal a comparative anti-hyperglycemic effect of crude leaf oregano extract to acarbose only a 1-hour post prandial glucose test using glucose test strip; negative results were noted at 30-min post prandial test. The degree of anti-hyperglycemic activity of oregano is time dependent, as analyzed using paired t-test. This is seen when the mean differences of the samples showed the t-value for trial 1, is above the critical limit of 2,776, which is 7,452 while in trial 2, they t-value is at o.991. However, the degree of anti-hyperglycemic activity of acabose using 1-hr and using 30-min post prandial glucose tests is not limited to the two trials as it showed high efficacy for both. t-values for acarbose in trial 1 and 2 are 5.888 and 3.871, respectively, which are both above critical limit of 2,776. Paired t-test results are using degrees of freedom of 4 at 95% confidence level. Previous researches link these anti-hyperglycemic activities of oregano crude leaf extract to its active components and through the antioxidant properties of soe of its active components, which may intern reduce hyperglycemia and may be of importaance to multiple goals of microvascular and metabolic risks reduction. To end, the oregano crude leaf extract offers a promising potential in the development of a natural remedy in the control of hyperglycemia.
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Target audience note Department of Pharmacology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Macam, Jonirei
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Personal name Macarambon, Al-Maruf
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Personal name Manuel, Mary Ann
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Personal name Mendoza, Ina Bianca
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Personal name Miranda, Michael
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Personal name Munar, Marvin
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Personal name Oaferina, Maharlika
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Personal name Olarte, Claire Joy
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Personal name Opinion, Freida ann
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Personal name Peralta, Emmanuel
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Personal name Perez, Ma. Lourdes
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Personal name Promentilla, Shella May
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Personal name Puzon, Eufronia Apple
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Personal name Remegio, Dennis
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Personal name Rosario, Ma. Ann Claire
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Personal name Rugay, Vincent Paolo
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Personal name Tapales, Earl Andrei
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Personal name Veracruz, Mary Rose
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Personal name Yamballa Wilson
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Personal name Yusay, Julie Christy
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Date last checked out Price effective from Koha item type
    Library of Congress Classification     Far Eastern University - Nicanor Reyes Medical Foundation Far Eastern University - Nicanor Reyes Medical Foundation Theses 02/11/2015 1 MPHAR20070001 T000811 11/26/2018 11/26/2018 07/22/2016 Theses