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Olfactory neuroblastoma in infancy "the great pretender" / Katherine Ann M. Peralta.

By: Language: English Publication details: Fairview, Quezon City Department of Child Health, FEU-NRMF, 2017Description: illustations and photos (colored); (in folder)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
LOC classification:
  • CH20170002
Summary: ABSTRACT: Esthesioneuroblastoma or olfactory neuroblastoma is an uncommon neuro-ectodermal tumor. Its biological activity ranges from indolent growth to local recurrence and rapid widespread metastasis. Treatment options consist of surgical resection followed by radiation therapy for primary lesions and the addition of chemotherapy for advanced, recurrent, or metastatic lesions. Patients often present with nasal obstruction, rhinorrhea, recurrent epistaxis, or anosmia. Olfactory neuroblastoma commonly occurs in the 2nd and 5th decade of life. Treatment options consist of surgical followed by radiation therapy for primary lesions and the addition of chemotherapy for advanced, recurrent, or metastatic lesions.This is a case of an 8 month-old female infantwho presented with epistaxis and a rapidly enlarging right maxiallary mass. CT Scan, MRI with contrast, and biopsy of the antral mass were done. Rhabdomyosarcoma,Neuroblastoma, Ewing's Sarcoma/PNET, and Lymphoma were considered. Definitive diagnosis of an olfactory neuroblastoma was established through immuno-histochemical stains.
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Research Far Eastern University - Nicanor Reyes Medical Foundation Research CH20170002 (Browse shelf(Opens below)) Available R000550

Includes appendices and bibliographical references.

ABSTRACT: Esthesioneuroblastoma or olfactory neuroblastoma is an uncommon neuro-ectodermal tumor. Its biological activity ranges from indolent growth to local recurrence and rapid widespread metastasis. Treatment options consist of surgical resection followed by radiation therapy for primary lesions and the addition of chemotherapy for advanced, recurrent, or metastatic lesions. Patients often present with nasal obstruction, rhinorrhea, recurrent epistaxis, or anosmia. Olfactory neuroblastoma commonly occurs in the 2nd and 5th decade of life. Treatment options consist of surgical followed by radiation therapy for primary lesions and the addition of chemotherapy for advanced, recurrent, or metastatic lesions.This is a case of an 8 month-old female infantwho presented with epistaxis and a rapidly enlarging right maxiallary mass. CT Scan, MRI with contrast, and biopsy of the antral mass were done. Rhabdomyosarcoma,Neuroblastoma, Ewing's Sarcoma/PNET, and Lymphoma were considered. Definitive diagnosis of an olfactory neuroblastoma was established through immuno-histochemical stains.

Research - Department of Child Health

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