Abdominal dermis fat graft as orbital implant for primary enucleation and post-enucleation syndrome / Ken B. Dela Cruz and Ma. Donna Santiago.

Includes appendices and bibliographical references.

Abstract: The Study aims to determine the effect of using autologous abdominal dermis fat graft as orbital implant for primary enucleation and post-enucleation syndrome patients, seen in a tertiary hospital from the year 2013 to 2017. This is a case study series study design. The study population consists of patients seen who underwent enucleation with autologus dermis fat graft implantation from January 2013 to December 2017 from the Charity Out-patient Department of Far Eastern University Nicanor Reyes Medical Faoundation (FEU-NRMF) or any consultants' clinic affiliated with FEU-NRMFwho fulfills criteria. A comprehensive medical records review was done to include all patients seen from January 2013 to December 2017 in the Charity Out-patient Department or Emergency Department or any consultants' clinic affiliated with FEU-NRMF who fulfilled eligibility criteria in the study. A total of nine (9) patients were entered in the study with an average age of 45.33 years, mostly males with a male to female ratio of 7:2. Etimology or the reason for undergoing procedure are globe rupture, and pthisis bulbi, among others. In terms of functional outcome, eight (8) patients in the study had 100% motility, one (1) one patient had 50% motility. All patients had complete implant coaptation and complete apposition of the eyelids. All of these parameters show good functional outcome of patients who underwent grafting of autologous dermis fat. For aesthetic outcome, all patients had orbital symmetry of 50% or more, present lid crease and good sulcus depth. These findings likewise suggests good overall aesthetic outcome. Complications common in using dermis fat grafting during enucleation such as infection, dehiscence, graft rejection and contracted socket were not seen in any of the patients in the study. Only one (1) patient had minimal hair growth postoperatively, which was immediately addressed with laser epilation. The use of autologous dermis fat graft as orbital implant in enucleation procedure and repair of post-enucleation syndrome results to good functional and aesthetic outcome. Complications are rare postoperatively, of which are only minor complications (namely minimal hair growth)which can be addressed immediately with no long term untoward and or debilitating effects to the patient. This study has limited number of subjects owing to the rarity of the case and the novel nature of the procedure. It is recommended to continue reporting findings for the subsequent cases of DFG implantation in enucleation to better describe this procedure and hopefully be able to use the data to correlate findings and factors associated to the outcomes of future cases of the new technique.

Research - Department of Ophthalmology