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Atypical metastatic pattern of cervical carcinoma: a case report / Amier Dayle A. Lopez.

Contributor(s): Language: english Publication details: Fairview, Quezon City: Department od Obstetrics and Gynecology, FEU-NRMF, 2020.Description: photos; with flash drive (soft copy). (in folder)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
Subject(s): LOC classification:
  • OB 2020 0006
Summary: Abstract: Cervical cancer is one of the leading cause of cancer related deaths among Filipino women. High risk papillomavirus types 16 and 18 are consistently found in women with cervical malignancy. It is generally assumed that virtually all squamous cell carcinomas are associated with persistent high risk HPV infection. Cervical cancer progress and spread in an orderly fashion, skip metastases is considered an atypical presentation for the disease and is therefore a rare occurrence. Advanced stage cervical carcinoma almost always presents either with abdominal vaginal bleeding or with malodorous vaginal discharge. Around 9% of total reported cases of cervical cancer is diagnosed at advanced stage. We present in this paper, a rare case of a 35-year-old, nulligravid, who presented almost silently with stage IVB cervical cancer. Histopathology showed poorly differentiated squamous cell carcinoma of the cervix with metastatic deposit in the uterus, parametria, ovaries appendix, omentum, and the peritoneal cavity. Its unusual presentation and pattern of spread makes the diagnosis a controversy.
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Includes appendices and bibliographical references.

Abstract: Cervical cancer is one of the leading cause of cancer related deaths among Filipino women. High risk papillomavirus types 16 and 18 are consistently found in women with cervical malignancy. It is generally assumed that virtually all squamous cell carcinomas are associated with persistent high risk HPV infection. Cervical cancer progress and spread in an orderly fashion, skip metastases is considered an atypical presentation for the disease and is therefore a rare occurrence. Advanced stage cervical carcinoma almost always presents either with abdominal vaginal bleeding or with malodorous vaginal discharge. Around 9% of total reported cases of cervical cancer is diagnosed at advanced stage. We present in this paper, a rare case of a 35-year-old, nulligravid, who presented almost silently with stage IVB cervical cancer. Histopathology showed poorly differentiated squamous cell carcinoma of the cervix with metastatic deposit in the uterus, parametria, ovaries appendix, omentum, and the peritoneal cavity. Its unusual presentation and pattern of spread makes the diagnosis a controversy.

Research - Department of Obstetrics & Gynecology

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