The Effects of sugammadex on emergence agitation on patients undergoing abdominal surgeries under general anesthesia / Sarah Samantha C. Obida and Arvin Vincent Palomar.

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Language: english Publication details: Fairview, Quezon City: Department of Anesthesiology, FEU-NRMF, 2019.Description: 38 pages: illustrations, tables; (in folder) with CD (soft copy)Content type:

text

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unmediated

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volume

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ANES 2019 0006

Summary: Abstract: Difficulty of breathing during emergence of anesthesia has been reported as a possible cause for emergence agitation. We investigated administrating sugammadex will reduce the incidence of emergence agitation in a randomized, double-blinded stud. A hundred and twenty American society of Anesthesiologist (ASA) I and II adults for elective abdominal surgery under general anesthesia, maintained on fentanyl, sevoflurane and rocuronium were randomly given 2 mg/kg sugammadex prior to extubation or await spontaneous recovery using a placebo. Emergence agitation was observed using the Richmond Agitation Sedation Scale. We found that 46.7% (n=28) in the sugammadex group (S group) were drowsy during the emergence of anesthesia, 40% were alert and calm, 6.7% were restless and 5% were lightly sedated. On the other hand, in the placebo group (P group) 55% were drowsy, 35% were alert and calm 5% were restless and 5% were lightly sedated. Using the Pearson Chi-square to compare the significance of emergence agitation between the sugammdex group and the placebo group shows a value of 1.753 (p-value>0.05). There is no statistical difference between the sugammdex and placebo group in terms of emergence agitation.

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Item type	Current library	Call number	Status	Notes	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Research	ANES 2019 0006 (Browse shelf(Opens below))	Available	with CD (soft copy)		R000951

Includes appendices and bibliographical references.

Abstract: Difficulty of breathing during emergence of anesthesia has been reported as a possible cause for emergence agitation. We investigated administrating sugammadex will reduce the incidence of emergence agitation in a randomized, double-blinded stud. A hundred and twenty American society of Anesthesiologist (ASA) I and II adults for elective abdominal surgery under general anesthesia, maintained on fentanyl, sevoflurane and rocuronium were randomly given 2 mg/kg sugammadex prior to extubation or await spontaneous recovery using a placebo. Emergence agitation was observed using the Richmond Agitation Sedation Scale. We found that 46.7% (n=28) in the sugammadex group (S group) were drowsy during the emergence of anesthesia, 40% were alert and calm, 6.7% were restless and 5% were lightly sedated. On the other hand, in the placebo group (P group) 55% were drowsy, 35% were alert and calm 5% were restless and 5% were lightly sedated. Using the Pearson Chi-square to compare the significance of emergence agitation between the sugammdex group and the placebo group shows a value of 1.753 (p-value>0.05). There is no statistical difference between the sugammdex and placebo group in terms of emergence agitation.

Research - Department of Anesthesiology

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