Double down : a recurrent myxoid liposarcoma with right inguinoscrotal extension - a case report / Jan Michael James F. Lazaro.

Includes appendices and bibliographical references.

Abstract: Liposarcoma is among the most common soft-tissue sarcomas in adults. Retroperitoneal liposarcomas are not usually detected early because of their location hence diagnosed at an advanced stage, and when they are, most are usually enormous in size due to the nature of the tumor. They can present in a multitude of ways depending on the size and subtype of liposarcoma. Myxoid retroperitoneal liposarcomas are highly locally recurrent with little to no metastatic potential and such, may present with inguinal herniation. Cases which present in such a way are rare, as such was logged in a study by Phu et al. 6 out of 168 patients with diagnosed retroperitoneal liposarcoma had inguinoscrotal extension. And this scarcity in cases brings out the need for discussion of betterment of future treatment. Here we report a case of a recurrent retroperitoneal myxoid liposarcoma with recurrent right inguinal hernia secondary to mass extension. A 70 year old male was re-admitted due to abdominal enlargement with concurrent right inguinioscrotal mass. The patient was a known case of recurrent retroperitoneal liposarcoma having undergone exploratory laparotomy with retroperitoneal mass excision (2016, 2018). Presently, the patient presented with a globular distended abdomen as well as enlarged scrotal mass. Chest and abdominopelvic CT scan with IV contrast were done. Patient's current case was deemed inoperable as well as high morbidity risk for neoadjuvant treatment due to size and extent hence surgery was put off and the patient was referred to palliative care for management until further notice. Diagnosis and prognosis of such recurrent retroperitoneal liposarcomas need the use of a combination of histopathology and specific imaging modalities to properly delineate tumor tissue margins since surgical resection is by far the gold standard therapy for most liposarcomas. Due to high recurrence rates, it is highly imperative for aggressive surveillance and complete tumor excision.

Research - Department of Radiology