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Association of anosmia and Covid-19 : a systematic review / Josef Carlo AngbuTe, Jules Reinier Ramos, and Danilo D. Deveza, Jr.

Contributor(s): Language: english Publication details: Fairview, Quezon City: Department of Otolaryngology, FEU-NRMF, 2022.Description: 26 pages: tables; (in folder) with flash drive (soft copy)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume26
Subject(s): LOC classification:
  • ENT 2022 0002
Summary: Abstract: Anosmia or "loss of smell" has been reported in patients with COVID-19 since pandemic began. We conducted a systematic review of the available literatures to evaluate the global the global incidence of anosmia in patients infected with COVID-19 and assess its relationship with severity including mortality. The study aims to discuss if anosmia can be used as a prognostic symptoms for COVID-19 moreover in determining the severity of the disease. A comprehensive search of the Medline/PubMed/, Elsevier/ Embase, Web of Science, LitCovid NIH, Proquest, Cochrane Library, and WHO COVID-19 databases was done. Data on the study characteristics ( anosmia, Covid19 prognosis and severity) were extracted following the "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" (PRISMA) guidelines. Newcastle-Ottawa scale (NOS) was use to evaluate the quality of the eligible articles. Pooled prevalence for COVID-19 with anosmia were calculated. A total of 77 articles were considered with 16, 761 COVID-19 patients, anosmia was reported in 8855 patients with a pooled prevalence of 50.4% globally (95% Cl:43.0%, 57.9%). The link between the occurrence of COVID-19 and anosmia were analyzed with 3834 COVID-19 patients with anosmia and 5714 non-COVID-19 patients (mainly SARS-CoV-2-like symptoms with negative RT-PCR). Anosmia is more common in COVID-19 patients with an OR of 9.31 (95%t Cl: 8.058, 10.754) and a p value of <0.001. "Loss of smell" is common in patients infected with COVID-19 and should be added as one of the key indicators in screening the population, it has been utilized as a preventive strategy where COVID-19 patients with anosmia should begin self-isolation. This will aid in the prevention of the disease's spread. Anosmia was also Connected with a somewhat better prognosis for the course of the disease.
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Includes appendices and bibliographical references.

Abstract: Anosmia or "loss of smell" has been reported in patients with COVID-19 since pandemic began. We conducted a systematic review of the available literatures to evaluate the global the global incidence of anosmia in patients infected with COVID-19 and assess its relationship with severity including mortality. The study aims to discuss if anosmia can be used as a prognostic symptoms for COVID-19 moreover in determining the severity of the disease. A comprehensive search of the Medline/PubMed/, Elsevier/ Embase, Web of Science, LitCovid NIH, Proquest, Cochrane Library, and WHO COVID-19 databases was done. Data on the study characteristics ( anosmia, Covid19 prognosis and severity) were extracted following the "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" (PRISMA) guidelines. Newcastle-Ottawa scale (NOS) was use to evaluate the quality of the eligible articles. Pooled prevalence for COVID-19 with anosmia were calculated. A total of 77 articles were considered with 16, 761 COVID-19 patients, anosmia was reported in 8855 patients with a pooled prevalence of 50.4% globally (95% Cl:43.0%, 57.9%). The link between the occurrence of COVID-19 and anosmia were analyzed with 3834 COVID-19 patients with anosmia and 5714 non-COVID-19 patients (mainly SARS-CoV-2-like symptoms with negative RT-PCR). Anosmia is more common in COVID-19 patients with an OR of 9.31 (95%t Cl: 8.058, 10.754) and a p value of <0.001. "Loss of smell" is common in patients infected with COVID-19 and should be added as one of the key indicators in screening the population, it has been utilized as a preventive strategy where COVID-19 patients with anosmia should begin self-isolation. This will aid in the prevention of the disease's spread. Anosmia was also Connected with a somewhat better prognosis for the course of the disease.

Research - Department of Otolaryngology

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