Image from Google Jackets

Risk factors of multisystem inflammatory syndrome in children: a systematic review and meta-analysis / [author]: Peralta, Katherine Ann M., Bautista, Eva llagan

Contributor(s): Language: English Publication details: Fairview, Quezon City: Department of Child health, FEU-NRMF, 2023Description: (in folder) with flash drive (soft copy)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
LOC classification:
  • CH 2023 0001
Summary: ABSTRACT: Background: It is now commonly known that children with COVID-19 have a multisystem inflammatory syndrome (MIS-C) that affects several organ systems. This review is an investigation and synthesis of evidence on risk factors affecting MIS-C among patients with COVID-19 which might have clinical implications on management of pediatric COVID-19 patients with MIS-C. Methods: PubMed, Cochrane COVID-19 Study Register, Scopus, WHO COVID-19 Database, Herdin Plus, and ACTA Medica Philippina were systematically searched from March 01, 2020 to May 31, 2023. Search terms included "COVID-19", "SARS-CoV-2", "coronavirus", "MIS-C", "multisystem inflammatory syndrome in children", "multisystem", "inflammatory", "Kawasaki disease", "pediatrics", "child", "children" and "risk factors Included observational studies were published in English and appraised using using Joanna Briggs Institute Sumari Tools. Meta-analysis using random effects was carried out and pooled effect estimates were expressed as Odds Ratio (OR) with 95% confidence intervals (95%CI). Results: Seven studies with a total of 1,861 pediatric patients were included in the review. Age above 9 years old (OR: 0.26; 95% Cl: 0.21, 0.31) and presence of underlying medical conditions (OR: 0.60; 95% Cl: 0.41, 0.87) were risk factors associated with MIS-C. Age above 9 years old as a risk factor showed considerable heterogeneity {I2 = 99.0%). Conclusion: Age (>9 years old) and underlying medical conditions increase the risk of developing MIS among the pediatric population. This review provides global insights into risk factors affecting MIS-C and further details are needed to validate the findings.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Call number Status Date due Barcode
Room Use Far Eastern University - Nicanor Reyes Medical Foundation CH 2023 0001 (Browse shelf(Opens below)) Available R000721
Browsing Far Eastern University - Nicanor Reyes Medical Foundation shelves Close shelf browser (Hides shelf browser)
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
CH 2022 0001 Factors affecting mortality among pediatric patients in the ICU tertiary training hospital / CH 2022 0002 Risk factors associated with severe COVID-19 among pediatric patients : a systematic review and meta-analysis / CH 2022 0003 Prevalence and profile of microcytic hypochromic anemia in pediatric population in a tertiary hospital / CH 2023 0001 Risk factors of multisystem inflammatory syndrome in children: a systematic review and meta-analysis / [author]: Peralta, Katherine Ann M., Bautista, Eva llagan CH 2023 0002 Clinical profile and outcomes of preterm neonates requiring mechanical ventilation: a 7-year review in a tertiary private hospital / [principal investigator]: Catapang, Jennifer Mari E. [co-author]: Nocheseda, Naomi S. CH 2023 0003 Clinico - demographic profile of pediatric patients with acute poisoning in a tertiary hospital during the covid-19 pandemic. / [author]: Bayta, Marian Kate DA. [co-author]: Geli, Tricia May V. CH 2023 0004 : Clinico-demographic profile of pediatric patients with febrile seizures in a tertiary private hospital in Fairview, Quezon city. / [Principal Investigator]: Delmendo, Charito P. [Co-Author]: Salamat-Millora, Hasmin B.

Includes bibliographical references

ABSTRACT: Background: It is now commonly known that children with COVID-19 have a multisystem inflammatory syndrome (MIS-C) that affects several organ systems. This review is an investigation and synthesis of evidence on risk factors affecting MIS-C among patients with COVID-19 which might have clinical implications on management of pediatric COVID-19 patients with MIS-C. Methods: PubMed, Cochrane COVID-19 Study Register, Scopus, WHO COVID-19 Database, Herdin Plus, and ACTA Medica Philippina were systematically searched from March 01, 2020 to May 31, 2023. Search terms included "COVID-19", "SARS-CoV-2", "coronavirus", "MIS-C", "multisystem inflammatory syndrome in children", "multisystem", "inflammatory", "Kawasaki disease", "pediatrics", "child", "children" and "risk factors Included observational studies were published in English and appraised using using Joanna Briggs Institute Sumari Tools. Meta-analysis using random effects was carried out and pooled effect estimates were expressed as Odds Ratio (OR) with 95% confidence intervals (95%CI). Results: Seven studies with a total of 1,861 pediatric patients were included in the review. Age above 9 years old (OR: 0.26; 95% Cl: 0.21, 0.31) and presence of underlying medical conditions (OR: 0.60; 95% Cl: 0.41, 0.87) were risk factors associated with MIS-C. Age above 9 years old as a risk factor showed considerable heterogeneity {I2 = 99.0%). Conclusion: Age (>9 years old) and underlying medical conditions increase the risk of developing MIS among the pediatric population. This review provides global insights into risk factors affecting MIS-C and further details are needed to validate the findings.

Research - Department of Child Health

There are no comments on this title.

to post a comment.