Risk factors of multisystem inflammatory syndrome in children: a systematic review and meta-analysis / [author]: Peralta, Katherine Ann M., Bautista, Eva llagan
Language: English Publication details: Fairview, Quezon City: Department of Child health, FEU-NRMF, 2023Description: (in folder) with flash drive (soft copy)Content type:- text
- unmediated
- volume
- CH 2023 0001
Item type | Current library | Call number | Status | Date due | Barcode | |
---|---|---|---|---|---|---|
Room Use | Far Eastern University - Nicanor Reyes Medical Foundation | CH 2023 0001 (Browse shelf(Opens below)) | Available | R000721 |
Browsing Far Eastern University - Nicanor Reyes Medical Foundation shelves Close shelf browser (Hides shelf browser)
Includes bibliographical references
ABSTRACT: Background: It is now commonly known that children with COVID-19 have a multisystem inflammatory syndrome (MIS-C) that affects several organ systems. This review is an investigation and synthesis of evidence on risk factors affecting MIS-C among patients with COVID-19 which might have clinical implications on management of pediatric COVID-19 patients with MIS-C. Methods: PubMed, Cochrane COVID-19 Study Register, Scopus, WHO COVID-19 Database, Herdin Plus, and ACTA Medica Philippina were systematically searched from March 01, 2020 to May 31, 2023. Search terms included "COVID-19", "SARS-CoV-2", "coronavirus", "MIS-C", "multisystem inflammatory syndrome in children", "multisystem", "inflammatory", "Kawasaki disease", "pediatrics", "child", "children" and "risk factors Included observational studies were published in English and appraised using using Joanna Briggs Institute Sumari Tools. Meta-analysis using random effects was carried out and pooled effect estimates were expressed as Odds Ratio (OR) with 95% confidence intervals (95%CI). Results: Seven studies with a total of 1,861 pediatric patients were included in the review. Age above 9 years old (OR: 0.26; 95% Cl: 0.21, 0.31) and presence of underlying medical conditions (OR: 0.60; 95% Cl: 0.41, 0.87) were risk factors associated with MIS-C. Age above 9 years old as a risk factor showed considerable heterogeneity {I2 = 99.0%). Conclusion: Age (>9 years old) and underlying medical conditions increase the risk of developing MIS among the pediatric population. This review provides global insights into risk factors affecting MIS-C and further details are needed to validate the findings.
Research - Department of Child Health
There are no comments on this title.