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Biphenotypic acute leukemia "mixed lineage" / Ramon Pocholo M. Naguiat.

Contributor(s): Language: english Publication details: Fairview, Quezon City: Department of Child Health, FEU-NRMF, 2007.Description: illustrations, tables, photos; (in folder)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
LOC classification:
  • CH 2007 0001
Summary: Abstract: This is a case of a 3 year old male with a 3 day history of intermittent moderate to high grade fever accomplished by cough, colds and difficulty in ambulation. Physical findings showed pallor, multiple cervical and inguinal lymphadenopathies, hepatomegaly, splenomegaly, petechiae on the anterior chest extending to the neck and groin areas and atrophy of lower extremities. Initial blood work-up revealed anemia, thrombocytopenia, leukopenia, neutropenia and lymphocytosis. Patient also had a past history of fall as well as exposure to an individual with active pulmonary tuberculosis. The patient was initially managed as a case of primary pulmonary tuberculosis to consider Pott`s Disease. Further workup revealed the presence of other disease entities. Flow cytometry of bone marrow aspirate showed immunologic findings consistent with a blast population showing both myeloid and B-lymphoid antigen expression, thus giving a diagnosis of Acute Biphenotypic Leukemia.
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Includes appendices and bibliographical references.

Abstract: This is a case of a 3 year old male with a 3 day history of intermittent moderate to high grade fever accomplished by cough, colds and difficulty in ambulation. Physical findings showed pallor, multiple cervical and inguinal lymphadenopathies, hepatomegaly, splenomegaly, petechiae on the anterior chest extending to the neck and groin areas and atrophy of lower extremities. Initial blood work-up revealed anemia, thrombocytopenia, leukopenia, neutropenia and lymphocytosis. Patient also had a past history of fall as well as exposure to an individual with active pulmonary tuberculosis. The patient was initially managed as a case of primary pulmonary tuberculosis to consider Pott`s Disease. Further workup revealed the presence of other disease entities. Flow cytometry of bone marrow aspirate showed immunologic findings consistent with a blast population showing both myeloid and B-lymphoid antigen expression, thus giving a diagnosis of Acute Biphenotypic Leukemia.

Research - Department of Child Health

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