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Comparison of the predictive value of CHADS2 and CHA2DS2 VASc among Filipino patients with coronary artery disease without atrial fibrillation for ischemic stroke admitted at FEU-NRMF from 2009-2012 a case control study / Ramil Y. Macapagal, Greg V. Dayrit and Ramon Pineda.

Contributor(s): Language: english Publication details: Fairview, Quezon City: Department of Internal Medicine, FEU-NRMF, 2013.Description: illustrations, tables; (in folder)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
LOC classification:
  • MED 2013 0008
Summary: Abstract: The CHADS2 score and other similar risk stratification schemes have proven useful in populations with known Atrial Fibrillation, the vast majority (85%) of ischemic occur in individuals without known Atrial Fibrillation. Patients with coronary heart disease (CHD) are at increased risk for stroke, and each of the component comorbidities of the CHADS2 score has been independently associated with stroke in large cohorts of patients with Coronary Heart Disease. CHA2DS2-VASc a new scoring system for risk stratification among atrial fibrillation for ischemic stroke is the modification of CHADS2 score. The study evaluates the CHADS score and CHA2DS2-VASc score for prediction of ischemic stroke/TIA among Filipino patients with Coronary Heart Disease without Atrial Fibrillation at FEU-NRMF. This is a Case Control Study. All Filipino patients with Coronary Artery Disease without Atrial Fibrillation with Ischemic Stoke (Case) or without Ischemic stroke (Control) were studied. CHADS2 (congestive heart failure (CHF), Hypertension, age≥ 75, diabetes (1 point each), and prior stoke or transient ischemic attack (TIA) (2 points) and the CHA2DS2-VASc (CHA2DS2-Vascular disease, Age 65-74 years, Sex category) (1 point each) score were calculated. A total of 752 subjects were studied, among them 188 subjects have ischemic stroke. In comparison of CHADS2 and CHAD2DS2-Vasc scoring between cases and controls, the results showed that there was a significant difference noted as proven by the p values 0.001 and 0.008 respectively. The CHAD2DS2-Vasc scoring of cases were significantly higher than controls. The CHADS2 risk score and the CHAD2DS2-Vasc risk score have a significant predictive value for Ischemic Stroke/TIA among patients with Coronary Artery Disease without Fibrillation. Also, CHAD2DS2-Vasc risk score comparing CHADS2 risk score due to its additional non-major stroke risk factors may be better in discriminating between patients at a low and high risk of stoke. The 2 scoring system may also have role in identification of high-risk individuals who may benefit from stroke prevention therapies or screening for silent atrial fibrillation.
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Item type Current library Call number Status Notes Date due Barcode
Research Far Eastern University - Nicanor Reyes Medical Foundation Research MED 2013 0008 (Browse shelf(Opens below)) Not For Loan draft R000890
Room Use Far Eastern University - Nicanor Reyes Medical Foundation Research MED 2013 0008 (Browse shelf(Opens below)) Available R000430

Includes bibliographical references.

Abstract: The CHADS2 score and other similar risk stratification schemes have proven useful in populations with known Atrial Fibrillation, the vast majority (85%) of ischemic occur in individuals without known Atrial Fibrillation. Patients with coronary heart disease (CHD) are at increased risk for stroke, and each of the component comorbidities of the CHADS2 score has been independently associated with stroke in large cohorts of patients with Coronary Heart Disease. CHA2DS2-VASc a new scoring system for risk stratification among atrial fibrillation for ischemic stroke is the modification of CHADS2 score. The study evaluates the CHADS score and CHA2DS2-VASc score for prediction of ischemic stroke/TIA among Filipino patients with Coronary Heart Disease without Atrial Fibrillation at FEU-NRMF. This is a Case Control Study. All Filipino patients with Coronary Artery Disease without Atrial Fibrillation with Ischemic Stoke (Case) or without Ischemic stroke (Control) were studied. CHADS2 (congestive heart failure (CHF), Hypertension, age≥ 75, diabetes (1 point each), and prior stoke or transient ischemic attack (TIA) (2 points) and the CHA2DS2-VASc (CHA2DS2-Vascular disease, Age 65-74 years, Sex category) (1 point each) score were calculated. A total of 752 subjects were studied, among them 188 subjects have ischemic stroke. In comparison of CHADS2 and CHAD2DS2-Vasc scoring between cases and controls, the results showed that there was a significant difference noted as proven by the p values 0.001 and 0.008 respectively. The CHAD2DS2-Vasc scoring of cases were significantly higher than controls. The CHADS2 risk score and the CHAD2DS2-Vasc risk score have a significant predictive value for Ischemic Stroke/TIA among patients with Coronary Artery Disease without Fibrillation. Also, CHAD2DS2-Vasc risk score comparing CHADS2 risk score due to its additional non-major stroke risk factors may be better in discriminating between patients at a low and high risk of stoke. The 2 scoring system may also have role in identification of high-risk individuals who may benefit from stroke prevention therapies or screening for silent atrial fibrillation.

Research - Department of Medicine

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