Severe pyridostigmine toxicity : a case report / Joan A. Serrano.

Contributor(s):

Serrano, Joan A., MD [author]

Language: english Publication details: Fairview, Quezon City: Department of Child Health, FEU-NRMF, 2010.Description: 18 pages: illustrations, tables; (in folder)Content type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

CH 2010 0007

Summary: Abstract: A 13 months old, female diagnosed with congenital myasthenia gravis at 9 months maintained on Pyridostigmine at 15 mg/paper tablet taken 5 times a day with sudden difficulty of breathing, drooling of saliva and seizure. Patient was admitted at the pediatric intensive care unit and inderwent atropinization. Pyridostigmine toxicity in myasthenia gravis is a rare condition since the drug is given to patients based on their signs and symptoms and computed according to their age and weight. Diagnosis can be made based on the presenting clinical signs and symptoms supported by an assay. However, in this case, pyridostigmine assay is available in our country thus, diagnostic dilemma sets in. Such incident warrants investigation and prompt intervention. At present, no standard mode of treatment was established to follow when such case is encountered.

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Item type	Current library	Call number	Status	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Research	CH 2010 0007 (Browse shelf(Opens below))	Available		R000048

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Previous	CH 2010 0005 Perinatal outcome of term neonates born to mothers with bacterial vaginosis at FEU-NRMF Medical Center /	CH 2010 0005 c.2 Perinatal outcome of term neonates born to mothers with bacterial vaginosis at FEU-NRMF Medical Center /	CH 2010 0006 Reversible posterior leukoencephalopathy syndrome in a 16 year old male : a case report /	CH 2010 0007 Severe pyridostigmine toxicity : a case report /	CH 2010 0008 Trisomy 21 with imperforate anus /	CH 2011 0001 Chronic kidney disease in 5 years old with congenital heart disease /	CH 2011 0002 Dengue hepatitis in a 6 - year old /	Next

Includes appendices and bibliographical references.

Abstract: A 13 months old, female diagnosed with congenital myasthenia gravis at 9 months maintained on Pyridostigmine at 15 mg/paper tablet taken 5 times a day with sudden difficulty of breathing, drooling of saliva and seizure. Patient was admitted at the pediatric intensive care unit and inderwent atropinization. Pyridostigmine toxicity in myasthenia gravis is a rare condition since the drug is given to patients based on their signs and symptoms and computed according to their age and weight. Diagnosis can be made based on the presenting clinical signs and symptoms supported by an assay. However, in this case, pyridostigmine assay is available in our country thus, diagnostic dilemma sets in. Such incident warrants investigation and prompt intervention. At present, no standard mode of treatment was established to follow when such case is encountered.

Research - Department of Child Health

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