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Efficacy of 23-valent pneumococcal vaccine in the outcome of pneumococcal bacteremia and hospitalization due to community acquired pneumonia in patients aged 60 years and older, seen at FEU-NRMF Medical Center emergency department from January 1, 2010 to January 1, 2011 : a retrospective cohort study / Marivi V. Allaga and Pio Esguerra.

Contributor(s): Language: english Publication details: Fairview, Quezon City: Department of Internal Medicine, FEU-NRMF, 2011.Description: 20 pages: (in folder)Content type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
LOC classification:
  • MED 2011 0004
Summary: Abstract: Streptococcus pneumonia is the cause of Pneumonia in older adults, but it remains whether the use of the Pneumococcal Polysaccharide Vaccine alters the overall risk of Community Acquired Pneumonia. In this retrospective cohort study 150 adults aged 60 years and older diagnosed with Community Acquired Pneumonia were assessed. The primary outcomes were (1) hospitalization due to Community Acquired Pneumonia (2) patients who are treated on an outpatient basis and (3) those who developed Pneumococcal bacteremia. The results showed no significant association between Pneumococcal vaccination status and hospitalization due to Community Acquired Pneumonia as proven by the p value of 0.51. Patients who were not vaccinated had higher risk of bacteremia (RR=1.81; 95% Cl = 0.93 - 5.19) hence it is cost effective to use the vaccine in older adults for the prevention of invasive Pneumococcal disease. These findings support that there is a reduced risk of Pneumococcal bacteremia, the outcome most directly linked to pneumococcal infection, among vaccinated persons who developed Community Acquired Pneumonia and no relation between the risk of hospitalization due to Community Acquired Pneumonia and the time since vaccination.
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Research Far Eastern University - Nicanor Reyes Medical Foundation Research MED 2011 0004 (Browse shelf(Opens below)) Not For Loan draft R000678
Room Use Far Eastern University - Nicanor Reyes Medical Foundation Research MED 2011 0004 (Browse shelf(Opens below)) Available R000346
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MED20100010 Primary hyperaldosteronism a breakthrough case report / MED 2011 0002 Determination of ionized calcium level in type 2 diabetes mellitus patients compared to nondiabetic subjects at FEU-NRMF Medical Center from January to June 2011 : a prospective study / MED 2011 0002 Determination of ionized calcium level in type 2 diabetes mellitus patients compared to nondiabetic subjects at FEU-NRMF Medical Center from January to June 2011 : a prospective study / MED 2011 0004 Efficacy of 23-valent pneumococcal vaccine in the outcome of pneumococcal bacteremia and hospitalization due to community acquired pneumonia in patients aged 60 years and older, seen at FEU-NRMF Medical Center emergency department from January 1, 2010 to January 1, 2011 : a retrospective cohort study / MED 2011 0004 Efficacy of 23-valent pneumococcal vaccine in the outcome of pneumococcal bacteremia and hospitalization due to community acquired pneumonia in patients aged 60 years and older, seen at FEU-NRMF Medical Center emergency department from January 1, 2010 to January 1, 2011 : a retrospective cohort study / MED 2011 0006 The Efficacy of the lung in flute in decreasing cough and sputum frequency and severity using the cough and sputum assessment questionnaire (CASA-Q) in adult patients with acute exacerbations of chronic obstructive pulmonary disease seen at FEU-NRMF Medical Center from June - September 2011 / MED 2011 0008 The Relationship of lifestyle factors and metabolic syndrome among junior interns (Level IV) and postgraduate interns, 20 years of age and above at FEU-NRMF Medical Center from May 2010 - October 2011 /

Includes appendices and bibliographical references.

Abstract: Streptococcus pneumonia is the cause of Pneumonia in older adults, but it remains whether the use of the Pneumococcal Polysaccharide Vaccine alters the overall risk of Community Acquired Pneumonia. In this retrospective cohort study 150 adults aged 60 years and older diagnosed with Community Acquired Pneumonia were assessed. The primary outcomes were (1) hospitalization due to Community Acquired Pneumonia (2) patients who are treated on an outpatient basis and (3) those who developed Pneumococcal bacteremia. The results showed no significant association between Pneumococcal vaccination status and hospitalization due to Community Acquired Pneumonia as proven by the p value of 0.51. Patients who were not vaccinated had higher risk of bacteremia (RR=1.81; 95% Cl = 0.93 - 5.19) hence it is cost effective to use the vaccine in older adults for the prevention of invasive Pneumococcal disease. These findings support that there is a reduced risk of Pneumococcal bacteremia, the outcome most directly linked to pneumococcal infection, among vaccinated persons who developed Community Acquired Pneumonia and no relation between the risk of hospitalization due to Community Acquired Pneumonia and the time since vaccination.

Research - Department of Medicine

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