Image from Google Jackets

A COMPARATIVE STUDY ON THE ANTISPASMODIC EFFECT OF GUYABANO (ANNONA MURICATA) LEAVES EXTRACT AND ATROPINE ON THE LOWER GASTROINTESTINAL TRACT OF SWISS MICE

By: Contributor(s): Language: English Publication details: Quezon City FEU-NRMF NDDescription: 22 pContent type:
  • Text
Media type:
  • Unmediated
Carrier type:
  • Volume
LOC classification:
  • MPHARND0014
Summary: ABSTRACT: The Leaves of Guyabano (Annona muricata, Linn.) which were proven to have an anti-spasmodic activity in previous studies made by different researchers, were compared to the anti-spasmodic effect of Atropine sulfate. The leaves collected were air dried for two weeks and ground using a blender. The ground leaves were soaked in 80% ethyl alcohol for four days. The extract were purified and boiled until it becomes thick and syrupy. The concentrated extract was diluted with NSS to yield a 30% concentration. The effectivity of the 30% guyabano extract was tested using Swiss mice. The Swiss mice with an average of 20 grams in weight was used. It was compared with a 0.2 ml dose Atropine sulfate. The Charcoal tracings on the small intestines of the Swiss mice with the extract showed significant anti-spasmodic effectivity.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Call number Status Date due Barcode
Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHARND0014c.1 (Browse shelf(Opens below)) Available T000913
Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHARND0014c.2 (Browse shelf(Opens below)) Available T000914

ABSTRACT: The Leaves of Guyabano (Annona muricata, Linn.) which were proven to have an anti-spasmodic activity in previous studies made by different researchers, were compared to the anti-spasmodic effect of Atropine sulfate. The leaves collected were air dried for two weeks and ground using a blender. The ground leaves were soaked in 80% ethyl alcohol for four days. The extract were purified and boiled until it becomes thick and syrupy. The concentrated extract was diluted with NSS to yield a 30% concentration. The effectivity of the 30% guyabano extract was tested using Swiss mice. The Swiss mice with an average of 20 grams in weight was used. It was compared with a 0.2 ml dose Atropine sulfate. The Charcoal tracings on the small intestines of the Swiss mice with the extract showed significant anti-spasmodic effectivity.

Department of Pharmacology

There are no comments on this title.

to post a comment.