Image from Google Jackets

A COMPARATIVE STUDY OF THE ANTI-PYRETIC EFFECTS OF THE CRUDE EXTRACT OF PORTULACA OLERACEA (GULASIMAN) WITH AN ESTABLISHED ANTIPYRETIC DRUG, PARACETAMOL (TEMPRA), TO FEVER-INDUCED RABBITS.

By: Contributor(s): Language: English Producer: NDDescription: NO NO. OF PAGESContent type:
  • Text
Media type:
  • Unmediated
Carrier type:
  • Volume
LOC classification:
  • THE M-PHAR ND 0016
Dissertation note: Pharmacology Thesis Summary: Portulaca oleracea (Gulasiman) extract, which showed antipyretic effects from a previous experiment, was tested at different dose levels (158.5 mg/kg BW, 630.9 mg/kg BW, and 2511 mg/kg BW) to fever-induced rabbits to determine the concentration that is closest to the antipyretic effect obtained from a commercial drug, Paracetamol (Tempra) The study showed that a dose of 158.5 mg/kg BW had no significant anti-pyretic effects, while significant anti-pyretic effects were noted at doses of 630.9 mg/kg BW and 2511 mg/kg BW. The latter shows the value closest to that of Paracetamol (Tempra) Although all dose levels showed anti-pyretic effects, statistical analysis revealed that Tempra had a greater fever-reducing effect than Portulaca oleracea. Statistical significance was confirmed using ANOVA.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Call number Status Date due Barcode
Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHARND0016c.1 (Browse shelf(Opens below)) Available T000916
Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHARND0016c.2 (Browse shelf(Opens below)) Available T000917

Pharmacology Thesis

Portulaca oleracea (Gulasiman) extract, which showed antipyretic effects from a previous experiment, was tested at different dose levels (158.5 mg/kg BW, 630.9 mg/kg BW, and 2511 mg/kg BW) to fever-induced rabbits to determine the concentration that is closest to the antipyretic effect obtained from a commercial drug, Paracetamol (Tempra) The study showed that a dose of 158.5 mg/kg BW had no significant anti-pyretic effects, while significant anti-pyretic effects were noted at doses of 630.9 mg/kg BW and 2511 mg/kg BW. The latter shows the value closest to that of Paracetamol (Tempra) Although all dose levels showed anti-pyretic effects, statistical analysis revealed that Tempra had a greater fever-reducing effect than Portulaca oleracea. Statistical significance was confirmed using ANOVA.

Department of Pharmacology

There are no comments on this title.

to post a comment.