A COMPARATIVE STUDY ON THE HYPOGLYCEMIC EFFECTS OF AMPALAYA TEA (MEMORDICA CHARANTIA) AND GLIBENCLAMIDE ON BLOOD GLUCOSE LEVELS OF MALE SWISS MICE

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Acorda, Leafar Marie SF

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Language: English Producer: 2002Description: 23 NO. OF PAGESContent type:

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THE M-PHAR 2002 0013

Dissertation note: Pharmacology Thesis Summary: The study was intended to determine the hypoglycemic activity of Ampalaya Tea on the blood glucose levels of male Swiss mice as compared to a standard oral hypoglycemic drug that is Glibenclamide. 30 male Swiss mice were divided in to 3 groups in which each group will receive orally a different solutions: ) 1 Group A (control) (distilled water; 2) Group B (Glibenclamide; 3) Group C ( Ampalaya Tea. Each group was subjected to Oral Glucose Tolerance Test (OGTT). Results obtained demonstrated a 33.89%, 49.9% average effectivity at 30 minutes, 34.31% at 60 minutes, 27.22%, 11.47% at 90 minutes after administration of the experimental solutions of Glibenclamide (Group B) and Ampalaya Tea (Group C) respectively. Therefore, Ampalaya Tea has a faster onset and shorter duration of action when compared to Glibenclamide which has a slower onset but longer and more sustained duration of action.

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Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20020013 (Browse shelf(Opens below))	Available		T000875

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Pharmacology Thesis

The study was intended to determine the hypoglycemic activity of Ampalaya Tea on the blood glucose levels of male Swiss mice as compared to a standard oral hypoglycemic drug that is Glibenclamide. 30 male Swiss mice were divided in to 3 groups in which each group will receive orally a different solutions: ) 1 Group A (control) (distilled water; 2) Group B (Glibenclamide; 3) Group C ( Ampalaya Tea. Each group was subjected to Oral Glucose Tolerance Test (OGTT). Results obtained demonstrated a 33.89%, 49.9% average effectivity at 30 minutes, 34.31% at 60 minutes, 27.22%, 11.47% at 90 minutes after administration of the experimental solutions of Glibenclamide (Group B) and Ampalaya Tea (Group C) respectively. Therefore, Ampalaya Tea has a faster onset and shorter duration of action when compared to Glibenclamide which has a slower onset but longer and more sustained duration of action.

Department of Pharmacology

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