STUDY ON THE ANTIHYPERGLYCEMIC POTENTIAL OF GARLIC (ALLIUM SATIVUM) SUPPLEMENT ON THE OGTT OF SECOND YEAR MEDICAL STUDENTS

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Publication details: QUEZON CITY FEU-NRMF 2004Description: 48 PAGESLOC classification:

MPHAR20040001

Summary: ABSTRACT: Garlic and its preparations have been widely recognized as agents for prevention and treatment of cardiovascular and other metabolic diseases. This study attempts to explore the possible antihyperglycemic actions of garlic. Transient hyperglycemia was induced in ten (10) healthy medical students, aged 22-35 years old by ingestion of 1.75g/kgBW glucose solution after fasting for at least eight (8) hours. A crossover experimental design was utilized where the subjects alternately received water and increasing doses of garlic capsules (2, 3, 5 capsules; equivalent to 1.5g garlic per capsule). The effect of the treatments on the blood glucose level of the students was measured using oral glucose tolerance test (OGTT) Results showed that treatment with 5 garlic capsules gave the most significant decrease in the blood glucose level followed by the treatment of 3 garlic capsules. Treatment with 2 garlic capsules, however, showed no significant decrease in the blood glucose levels of the subjects.

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Item type	Current library	Call number	Status	Date due	Barcode
Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20040001c.2 (Browse shelf(Opens below))	Available		T001745
Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20040001 (Browse shelf(Opens below))	Available		T000834

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ABSTRACT: Garlic and its preparations have been widely recognized as agents for prevention and treatment of cardiovascular and other metabolic diseases. This study attempts to explore the possible antihyperglycemic actions of garlic. Transient hyperglycemia was induced in ten (10) healthy medical students, aged 22-35 years old by ingestion of 1.75g/kgBW glucose solution after fasting for at least eight (8) hours. A crossover experimental design was utilized where the subjects alternately received water and increasing doses of garlic capsules (2, 3, 5 capsules; equivalent to 1.5g garlic per capsule). The effect of the treatments on the blood glucose level of the students was measured using oral glucose tolerance test (OGTT) Results showed that treatment with 5 garlic capsules gave the most significant decrease in the blood glucose level followed by the treatment of 3 garlic capsules. Treatment with 2 garlic capsules, however, showed no significant decrease in the blood glucose levels of the subjects.

Department of Pharmacology

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