A COMPARATIVE STUDY ON THE HYPOGLYCEMIC EFFECT OF OREGANO (ORIGANUM VULGARE) LEAF DECOCTION VERSUS ACARBOSE ON HYPERGLYCEMIC-INDUCED MALE INTERNATIONAL CANCER RESEARCH (ICR) MICE

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THE M-PHAR 2007 0002

Dissertation note: Pharmacology Thesis Summary: This study investigates the hypoglycemic effect of orally administered Oregano (Origanum vulgare) leaf decoction versus Acarbose on hyperglycemic-induced male International Cancer Research (ICR) mice at one hour and thirty minutes postprandial blood glucose. 15 male ICR mice were divided into three groups. Group A received distilled water.Group B received oral Acarbose and Group C received Oregano leaf decoction. Blood glucose levels were determined at one hour and thirty minutes interval. Statistical test used are Paired T-Test and One-way ANOVA to determine if Oregano leaf decoction and Acarbose exerts a significant hypoglycemic effect at 1 hour and 30 minutes postprandial. Yielded results showed that the hypoglycemic effect of Oregano leaf decoction and Acarbose on one hour postprandial blood glucose is comparable and a period of one hour is required for the hypoglycemic action of Oregano to take effect.

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Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20070002C.1 (Browse shelf(Opens below))	Available		T000812
Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20070002C.2 (Browse shelf(Opens below))	Available		T000813

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Pharmacology Thesis

This study investigates the hypoglycemic effect of orally administered Oregano (Origanum vulgare) leaf decoction versus Acarbose on hyperglycemic-induced male International Cancer Research (ICR) mice at one hour and thirty minutes postprandial blood glucose. 15 male ICR mice were divided into three groups. Group A received distilled water.Group B received oral Acarbose and Group C received Oregano leaf decoction. Blood glucose levels were determined at one hour and thirty minutes interval. Statistical test used are Paired T-Test and One-way ANOVA to determine if Oregano leaf decoction and Acarbose exerts a significant hypoglycemic effect at 1 hour and 30 minutes postprandial. Yielded results showed that the hypoglycemic effect of Oregano leaf decoction and Acarbose on one hour postprandial blood glucose is comparable and a period of one hour is required for the hypoglycemic action of Oregano to take effect.

Department of Pharmacology

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