Determination of wound healing property of banana leaf (Musa Paradisiaca L.) extract on burn induced rabbits (Oryctolagus Cuniculus) / Mary Aimee Wong, Stephanie Anne Abella, Shangrila Mae Dimol, Alexandra Nathalie Legaspi, Jenalyn Salasac, Mae Alumpe, Renz Adonis Aguilar, Wilfred Antonio, Catherine Christle Chong, Emanuel Joseph Cruz, Bryan Ismael Cueto, Christian Anthony Flosa, Christine Jane Hermo, John Rosello Madrid, Ma. Jeane Malabaguio, Julie Maron, Lady Arriane Obanos, Jay Punzalan, Theone Jarilyn Ramirez, Edgar Salem, Annie Solano, Aidelnorme Tiangco, Kenneth Tung, Marco Paulo Velante, Alvic Villanueva, Mathew Stevenson Ong, Durell Betita, Shieldon Calayan, Rayfred Francis Dagnalan, Ronnel Franco, Vanessa Oliveros, Josiephine Mendoza, Paula Xerxes Capati, Princess Espulgar, Nino Mangune and Reginald Kristian Santos.

Contributor(s):

Language: english Publication details: Fairview, Quezon City: Department of Pharmacology, FEU-NRMF, 2009.Description: 48 pages: illustrations, tables; 28 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

M PHAR 2009 0004

Summary: Abstract: The study aims to compare the wound healing effects of Banana leaf extract ointment, Silver sulfadiazine, and Banana leaf decoction before( 1st day) and after ( 14th day) treatment on burn-induced rabbits. The research evaluate the healing properties as to Acute and Chronic inflammatory cell reaction, Epithelialization, and Neovascularization as parameters. Two biopsies were done to evaluate these histologic markers. The first biopsy was done after 24 hours of burn wound induction without receiving any treatment yet. The second biopsy was done after 14 days of treatment. Specimens are submitted for histopathologic analysis. Slides were read by a pathologist, graded and recorded. The results were computed using paired t-test(one-tail). And the calculated results demonstrate that none of the groups show significant difference on Acute and Chronic Inflammatory cell reaction, and Groups A and D equally showed significant difference on epithelialization before and after treatment. Only Group D showed a significant difference on neovascularization compared before and after treatment. Group D is the only group observed to be most effective in wound healing significantly promoting 2 parameters, epithelialization and neovascularization after 14 days of treatment.

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Holdings
Item type	Current library	Call number	Status	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Theses	M PHAR 2009 0004 c.2 (Browse shelf(Opens below))	Available		T001215
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Theses	M PHAR 2009 0004 c.1 (Browse shelf(Opens below))	Available		T000823

Includes appendices and bibliographical references.

Abstract: The study aims to compare the wound healing effects of Banana leaf extract ointment, Silver sulfadiazine, and Banana leaf decoction before( 1st day) and after ( 14th day) treatment on burn-induced rabbits. The research evaluate the healing properties as to Acute and Chronic inflammatory cell reaction, Epithelialization, and Neovascularization as parameters. Two biopsies were done to evaluate these histologic markers. The first biopsy was done after 24 hours of burn wound induction without receiving any treatment yet. The second biopsy was done after 14 days of treatment. Specimens are submitted for histopathologic analysis. Slides were read by a pathologist, graded and recorded. The results were computed using paired t-test(one-tail). And the calculated results demonstrate that none of the groups show significant difference on Acute and Chronic Inflammatory cell reaction, and Groups A and D equally showed significant difference on epithelialization before and after treatment. Only Group D showed a significant difference on neovascularization compared before and after treatment. Group D is the only group observed to be most effective in wound healing significantly promoting 2 parameters, epithelialization and neovascularization after 14 days of treatment.

Thesis - Department of Pharmacology

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