A COMPARATIVE STUDY ON THE EFFICACY OF TONGYITANG HYPOGLYCEMIC CAPSULE AND METFORMIN - GLIBENCLAMIDE IN REDUCING BLOOD GLUCOSE LEVELS OF GLUCOSE - INDUCED HYPERGLYCEMIA IN RATS

By:

Cruz, Abraham Daniel C., M.D

Contributor(s):

2nd year A Second Semester

Publication details: QUEZON CITY FEU-NRMF 2012Description: 38 PAGESLOC classification:

MPHAR20120005

Summary: ABSTRACT: The potential glucose-lowering effect of Tongyitang capsules against elevated levels of glucose in Rattus norvegicus rats was investigated in this study. Glucose solution was utilized to induce hyperglycemia in three test groups. These were tested against Metformin-Glibenclamide and distilled water as positive and negative controls, respectively. Blood glucose levels extracted from the tail vein were measured using a glucometer. Blood glucose levels were measured at the different time intervals. Hypoglycemic effects were observed in both Tongyitang and Metformin-Glibenclamide treated groups, however consistent hypoglycemic effects were seen more in the former group.

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Item type	Current library	Call number	Status	Barcode
Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20120005C.1 (Browse shelf(Opens below))	Available	T000894
Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20120005C.2 (Browse shelf(Opens below))	Available	T000895
Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MPHAR20120005C.3 (Browse shelf(Opens below))	Available	T000896

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ABSTRACT: The potential glucose-lowering effect of Tongyitang capsules against elevated levels of glucose in Rattus norvegicus rats was investigated in this study. Glucose solution was utilized to induce hyperglycemia in three test groups. These were tested against Metformin-Glibenclamide and distilled water as positive and negative controls, respectively. Blood glucose levels extracted from the tail vein were measured using a glucometer. Blood glucose levels were measured at the different time intervals. Hypoglycemic effects were observed in both Tongyitang and Metformin-Glibenclamide treated groups, however consistent hypoglycemic effects were seen more in the former group.

Department of Pharmacology

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