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A STUDY ON THE POTENTIATING EFFECT OF THE DECOCTION OF MORINGA OLEIFERA (MALUNGGAY) LEAF ON THE SEDATIVE ACTIVITY OF DIAZEPAM ON MALE SPRAGUE DAWLEY RATS

Contributor(s): Publication details: QUEZON CITY FEU-NRMF March 2013Description: 26 PAGESLOC classification:
  • MPHAR20130006
Summary: ABSTRACT: This study aims to determine the potentiating effect of the decoction of Moringa oleifera leaves on the sedative activity of Diazepam on male Sprague Dawley rats. Fifteen rats were divided into three groups of five. The first groups of rats were given the standard drug, Diazepam; the second group was administered with the decoction of M. oleifera aqueous solution. The aqueous extract of M. oleifera leaves exert a potentiating effect on Diazepan when they were administered. The researchers conclude that the aqueous extract potentiates Diazepan, and as such, should be further investigated to prevent health risks with other drugs.
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Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHAR20130006C.1 (Browse shelf(Opens below)) Available T001025
Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHAR20130006C.2 (Browse shelf(Opens below)) Available T001026
Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHAR20130006C.3 (Browse shelf(Opens below)) Available T001027
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MPHAR20130005C.2 A STUDY ON THE ANTILIPIDEMIC EFFECT OF CYMPBOPOGON CITRATES (TANGLAD) EXTRACT IN COMBINATION WITH SIMVASTATIN ON THE LOW DENSITY LIPOPROTEIN LEVELS OF HYPERCHOLESTEROLEMIC-INDUCED RATS MPHAR20130005C.3 A STUDY ON THE ANTILIPIDEMIC EFFECT OF CYMPBOPOGON CITRATES (TANGLAD) EXTRACT IN COMBINATION WITH SIMVASTATIN ON THE LOW DENSITY LIPOPROTEIN LEVELS OF HYPERCHOLESTEROLEMIC-INDUCED RATS MPHAR20130006C.1 A STUDY ON THE POTENTIATING EFFECT OF THE DECOCTION OF MORINGA OLEIFERA (MALUNGGAY) LEAF ON THE SEDATIVE ACTIVITY OF DIAZEPAM ON MALE SPRAGUE DAWLEY RATS MPHAR20130006C.2 A STUDY ON THE POTENTIATING EFFECT OF THE DECOCTION OF MORINGA OLEIFERA (MALUNGGAY) LEAF ON THE SEDATIVE ACTIVITY OF DIAZEPAM ON MALE SPRAGUE DAWLEY RATS MPHAR20130006C.3 A STUDY ON THE POTENTIATING EFFECT OF THE DECOCTION OF MORINGA OLEIFERA (MALUNGGAY) LEAF ON THE SEDATIVE ACTIVITY OF DIAZEPAM ON MALE SPRAGUE DAWLEY RATS MPHAR20130007C.1 STUDY ON THE SERUM URIC ACID LOWERING EFFECTS OF MANGIFERA INDICA (MANGO) METHANOLIC EXOCARP EXTRACT AND ALLOPURINOL ON MALE SPRAGUE-DAWLEY RATS MPHAR20130007C.2 STUDY ON THE SERUM URIC ACID LOWERING EFFECTS OF MANGIFERA INDICA (MANGO) METHANOLIC EXOCARP EXTRACT AND ALLOPURINOL ON MALE SPRAGUE-DAWLEY RATS

ABSTRACT: This study aims to determine the potentiating effect of the decoction of Moringa oleifera leaves on the sedative activity of Diazepam on male Sprague Dawley rats. Fifteen rats were divided into three groups of five. The first groups of rats were given the standard drug, Diazepam; the second group was administered with the decoction of M. oleifera aqueous solution. The aqueous extract of M. oleifera leaves exert a potentiating effect on Diazepan when they were administered. The researchers conclude that the aqueous extract potentiates Diazepan, and as such, should be further investigated to prevent health risks with other drugs.

Department of Pharmacology

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