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Clinical pharmacokinetics and pharmacodynamics : concepts and applications / Malcolm Rowland, Thomas N. Tozer

By: Contributor(s): Publication details: Philadelphia : Wolters Kluwer Health/Lippincott William & Wilkins, c2011Edition: Fourth EditionDescription: xxii, 839 p. : ill. ; 26 cmISBN:
  • 9780781750097
  • 0781750091
Subject(s): DDC classification:
  • 615/.7 22
LOC classification:
  • RM 301.5 .R695 2011
  • RM301.5 .R68 2011
NLM classification:
  • 2010 I-082
  • QV 38
Online resources:
Contents:
Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data
Review: "Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject."--BOOK JACKET
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Holdings
Item type Current library Call number Status Date due Barcode
Books Overnight Far Eastern University - Nicanor Reyes Medical Foundation Circulation Section RM 301.5 .R695 2011 (Browse shelf(Opens below)) Available 0008042

Rev. ed. of: Clinical pharmacokinetics. 1995

Includes index

Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data

"Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject."--BOOK JACKET

School of Pharmacy Department of Pharmacology

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