Determining Dual Use Concern of FEU-NRMF School of Medical Laboratory Science Researches / Nino Candava ; Joanne De Jesus ; Ciarleen De Ramos ; Alyssa Leoncio ; Sarah Madike ; Hazel Maga ; Ivonne Melano ; Rod Solante ; Geanne Su and Katrina Tiga.

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Publication details: Fairview, Quezon City School of Medical Technology, FEU-NRMF 2016Description: 30 pages: tables; 28 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

MT 2016 0013

Summary: Dual research of concern or DURC is a life science research that was used to give benefits and harm, either accidental or intentional. The latter benefit is the concern of science. This issue contains not only research and public health but also security, biotechnology and ethics, scientific publishing and public communications and wider issues related to society. (WHO) In this study, the FEU-NRMF school of Medical Laboratory Science faculty and students identified and determined the dual use concern of the researches. In addition, possible biosecurity risks using DURC were also identified. The result showed that 14 out of 36 researchers (38.89%) have the potential to have dual use concern. Category 1 (enhancing virulence of pathogens or toxins) and category 5 (altering the host range or tropism of a biological agent or toxin)were the most common categories in the DURCs assessed, having 57.14% each. Another category that was observed was category 4 (increasing the stability, transmissibility, or disseminating ability of a biological agent or toxin), which was evaluated in 35.71% of the DURC. All of the DURCs were using semi-advanced methods like autoclave, incubator, culture and sensitivity, and biosafety cabinet (equipment threshold level 2); and were categorized under the undergraduate level (expertise threshold level 1). With the equipment and expertise threshold, the biosecurity ranks of all the DURCs were calculated to be level 2 (mild threat). The risk to benefit ratio of all the DURCs were assessed as 1:2, which means the benefits of the researches outweigh the possible risks assessed. Based on the findings, all of the evaluated experimental researches either undergraduate or semi-advanced equipment was used, dual use researches were not avoided. Lack of awareness of the DURCs may be a cause; therefore, awareness programs, vigilance on the part of the Ethics committee in evaluating the DURCS and policies regarding DURCs should be instituted.

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Theses	Far Eastern University - Nicanor Reyes Medical Foundation Theses	MT 2016 0013 (Browse shelf(Opens below))	Available		T001243

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Includes appendices and bibliographical references.

Dual research of concern or DURC is a life science research that was used to give benefits and harm, either accidental or intentional. The latter benefit is the concern of science. This issue contains not only research and public health but also security, biotechnology and ethics, scientific publishing and public communications and wider issues related to society. (WHO) In this study, the FEU-NRMF school of Medical Laboratory Science faculty and students identified and determined the dual use concern of the researches. In addition, possible biosecurity risks using DURC were also identified. The result showed that 14 out of 36 researchers (38.89%) have the potential to have dual use concern. Category 1 (enhancing virulence of pathogens or toxins) and category 5 (altering the host range or tropism of a biological agent or toxin)were the most common categories in the DURCs assessed, having 57.14% each. Another category that was observed was category 4 (increasing the stability, transmissibility, or disseminating ability of a biological agent or toxin), which was evaluated in 35.71% of the DURC. All of the DURCs were using semi-advanced methods like autoclave, incubator, culture and sensitivity, and biosafety cabinet (equipment threshold level 2); and were categorized under the undergraduate level (expertise threshold level 1). With the equipment and expertise threshold, the biosecurity ranks of all the DURCs were calculated to be level 2 (mild threat). The risk to benefit ratio of all the DURCs were assessed as 1:2, which means the benefits of the researches outweigh the possible risks assessed. Based on the findings, all of the evaluated experimental researches either undergraduate or semi-advanced equipment was used, dual use researches were not avoided. Lack of awareness of the DURCs may be a cause; therefore, awareness programs, vigilance on the part of the Ethics committee in evaluating the DURCS and policies regarding DURCs should be instituted.

Thesis - School of Medical Technology

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