The Effects of tawa-tawa (euphorbia hirta l.) crude extract in elevating the platelet the count of albino rats (rattus norvegicus albinus) / I C - 2.

Contributor(s):

I C - 2 [author]

Language: english Publication details: Fairview, Quezon City: Department of Biochemistry, FEU-NRMF, 2006.Description: 27 pages: illustrations, tables, photos; 28 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

M BIO 2006 0002

Summary: Abstract: According to a popular folklore in Mindanao, Tawa-tawa (Euphorbia hirta) has shown considerable effects in treating Dengue patients. Some doctors assumed that the mechanism for this was its ability to increase patient's platelet levels. However, the Department of Health has been cautious to prescribe the said herb to the public due to inadequate research works. The crude extract of tawa-tatwa was utilizaed in this study to determine its effect on the platelet counts of albino rats. The experimental method of research was utilized in the study. Crude extraction of the tawa-tawa plant (Euphorbia hirta L.) was done using rotary evaporator (rotavap). The crude extract, at different concentrations (50%, 75% 100%) was then introduced to female albino rats (Rattus norvegicus albinus). Initial platelet counts were taken prior to administration to establish a baseline. Platelet counts of the albino rats were then monitored for 8 hours following the two-hour interval format. The data were verified the Analysis of Variance (ANOVA). The statistical treatment showed that the average platelet count after an eight-hour monitoring ranges from 680 pc cu.mm to 820 per cu.mm. Experimental group gave no significant increase on the platelet count of albino rats. The significant difference in the platelet counts between the control and the experimental group was determined by the Analysis of Variance (ANOVA). The computed f-value was lesser than the tabular value at 0.05 level of significance. This verified that there was no significant difference on the changes of the platelet count of the experimental female albino rats compared with the controls.

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Item type	Current library	Call number	Status	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Theses	M BIO 2006 0002 (Browse shelf(Opens below))	Available		T001278

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Previous	M BIO 2000 0006 Glycemic index of local fiber sources /	M BIO 2000 0007 Comparative study of uric acid content between plant and animal foods /	M BIO 2006 0001 Cytotoxic activity of allyl-isothiocyanate extracted from brassica oleracea l. ar.capitata (common cabbage) against human lung non-small cell adenocarcinoma (A549) and human colorectal cancer cell COL2) using mtt prolifertion assay /	M BIO 2006 0002 The Effects of tawa-tawa (euphorbia hirta l.) crude extract in elevating the platelet the count of albino rats (rattus norvegicus albinus) /	M BIO 2006 0003 Preliminary study on the effect of lactobacillus fermentum on the blood cholesterol level among young adults /	M BIO 2006 0004 A Comparative study on the antibacterial properties of achyranthes aspera (hagor), blechum pyramidatum (dayang) and vernonia cinerea (tagulinaw) plant extracts on staphylococcus aureus and escherichia coli /	M BIO 2006 0005 A Comparison of the efficacy of different preparations of virgin coconut oil in preventing LDL oxidation on male mus musculus (white mice) /	Next

Includes appendices and bibliographical references.

Abstract: According to a popular folklore in Mindanao, Tawa-tawa (Euphorbia hirta) has shown considerable effects in treating Dengue patients. Some doctors assumed that the mechanism for this was its ability to increase patient's platelet levels. However, the Department of Health has been cautious to prescribe the said herb to the public due to inadequate research works. The crude extract of tawa-tatwa was utilizaed in this study to determine its effect on the platelet counts of albino rats. The experimental method of research was utilized in the study. Crude extraction of the tawa-tawa plant (Euphorbia hirta L.) was done using rotary evaporator (rotavap). The crude extract, at different concentrations (50%, 75% 100%) was then introduced to female albino rats (Rattus norvegicus albinus). Initial platelet counts were taken prior to administration to establish a baseline. Platelet counts of the albino rats were then monitored for 8 hours following the two-hour interval format. The data were verified the Analysis of Variance (ANOVA). The statistical treatment showed that the average platelet count after an eight-hour monitoring ranges from 680 pc cu.mm to 820 per cu.mm. Experimental group gave no significant increase on the platelet count of albino rats. The significant difference in the platelet counts between the control and the experimental group was determined by the Analysis of Variance (ANOVA). The computed f-value was lesser than the tabular value at 0.05 level of significance. This verified that there was no significant difference on the changes of the platelet count of the experimental female albino rats compared with the controls.

Thesis - Department of Biochemistry & Nutrition

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