Image from Google Jackets

Preliminary study on the effect of lactobacillus fermentum on the blood cholesterol level among young adults / Section A2.

Contributor(s): Language: english Publication details: Fairview, Quezon City: Department of Biochemistry, FEU-NRMF, 2006.Description: 109 pages: illustrations, tables, photos; 28 cmContent type:
  • rdacontent
Media type:
  • rdamedia
Carrier type:
  • rdacarrier
LOC classification:
  • M BIO 2006 0003
Summary: Abstract: The variability in the baseline cholesterol levels of 30 young adults was determined. Values ranged from 1.85 - 5.30 mmol / Liter. After a week under a high cholesterol diet, cholesterol levels of the young adults significantly increased (p<0.05). Values ranged from 2.61 - 6.55 mmol / Liter. Variability in the cholesterol levels is attributed to an each individuals unique biochemistry, physiology, lifestyle and even genetics. Fischer's Extract Test values conferred the responsive behavior of cholesterol level (increase or decrease) to the both the Probiotic drug and the placebo. The placebo had a greater effect on the behavior of cholesterol level on the 1st and 3rd dosage period (1 capsule / day and 3 capsules/ day, respectively), (1 - tailed Left-Sided Pr < = F 0.1648 and 1- Tailed Left Sided Pr < = F 0.1362, respectively). Probiotic effect on decreasing cholesterol level was significant (p < 0.25) at the 2nd dosage period (2 capsules/ day), (1- tailed Right-sided Pr <= F 0.02311). This confirms the cholesterol-lowering property of the Probiotic , which may be attributed to the bile-acid deconjugating property of the Lactobacillus fermentum. The Odds Ratio showed the taking the Probiotic drug twice a day more effective in lowering the cholesterol level (2.2857 with 95% confidence interval- 1.3519, 10.0185). Odds ratio for the 1st and 3rd dosage period showed the greater effect of the placebo, though only half as potent as compared to the cholesterol- lowering activity during 2nd dosage period (0.1964 with 95% confidence interval - 0.0191, 2.0174 and 0.333 with confidence interval - 0.0751, 1.4787, respectively). These further confer the functionality of the Probiotic drug, especially at two capsules per day, not only in improving the intestinal environment for better absorption, but also in lowering blood cholesterol levels. Furthermore, Probiotics can potentially decrease the risk of having cholesterol-related diseases. Several factors such as individual differences in biochemistry, physiology, compliance may contribute to the variable behavior of cholesterol levels in response to both the placebo and Probiotics.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Call number Status Date due Barcode
Room Use Far Eastern University - Nicanor Reyes Medical Foundation Theses M BIO 2006 0003 (Browse shelf(Opens below)) Available T001279
Browsing Far Eastern University - Nicanor Reyes Medical Foundation shelves, Shelving location: Theses Close shelf browser (Hides shelf browser)
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
No cover image available
M BIO 2000 0007 Comparative study of uric acid content between plant and animal foods / M BIO 2006 0001 Cytotoxic activity of allyl-isothiocyanate extracted from brassica oleracea l. ar.capitata (common cabbage) against human lung non-small cell adenocarcinoma (A549) and human colorectal cancer cell COL2) using mtt prolifertion assay / M BIO 2006 0002 The Effects of tawa-tawa (euphorbia hirta l.) crude extract in elevating the platelet the count of albino rats (rattus norvegicus albinus) / M BIO 2006 0003 Preliminary study on the effect of lactobacillus fermentum on the blood cholesterol level among young adults / M BIO 2006 0004 A Comparative study on the antibacterial properties of achyranthes aspera (hagor), blechum pyramidatum (dayang) and vernonia cinerea (tagulinaw) plant extracts on staphylococcus aureus and escherichia coli / M BIO 2006 0005 A Comparison of the efficacy of different preparations of virgin coconut oil in preventing LDL oxidation on male mus musculus (white mice) / M BIO 2011 0001 A Comparative study on the total phenolic content and scavenging activity of antioxidants from seeds of citrus microcarpa (calamansi), citrus sinensis (orange) and citrus aurantium (dalandan) /

Includes appendices and bibliographical references.

Abstract: The variability in the baseline cholesterol levels of 30 young adults was determined. Values ranged from 1.85 - 5.30 mmol / Liter. After a week under a high cholesterol diet, cholesterol levels of the young adults significantly increased (p<0.05). Values ranged from 2.61 - 6.55 mmol / Liter. Variability in the cholesterol levels is attributed to an each individuals unique biochemistry, physiology, lifestyle and even genetics. Fischer's Extract Test values conferred the responsive behavior of cholesterol level (increase or decrease) to the both the Probiotic drug and the placebo. The placebo had a greater effect on the behavior of cholesterol level on the 1st and 3rd dosage period (1 capsule / day and 3 capsules/ day, respectively), (1 - tailed Left-Sided Pr < = F 0.1648 and 1- Tailed Left Sided Pr < = F 0.1362, respectively). Probiotic effect on decreasing cholesterol level was significant (p < 0.25) at the 2nd dosage period (2 capsules/ day), (1- tailed Right-sided Pr <= F 0.02311). This confirms the cholesterol-lowering property of the Probiotic , which may be attributed to the bile-acid deconjugating property of the Lactobacillus fermentum. The Odds Ratio showed the taking the Probiotic drug twice a day more effective in lowering the cholesterol level (2.2857 with 95% confidence interval- 1.3519, 10.0185). Odds ratio for the 1st and 3rd dosage period showed the greater effect of the placebo, though only half as potent as compared to the cholesterol- lowering activity during 2nd dosage period (0.1964 with 95% confidence interval - 0.0191, 2.0174 and 0.333 with confidence interval - 0.0751, 1.4787, respectively). These further confer the functionality of the Probiotic drug, especially at two capsules per day, not only in improving the intestinal environment for better absorption, but also in lowering blood cholesterol levels. Furthermore, Probiotics can potentially decrease the risk of having cholesterol-related diseases. Several factors such as individual differences in biochemistry, physiology, compliance may contribute to the variable behavior of cholesterol levels in response to both the placebo and Probiotics.

Thesis - Department of Biochemistry & Nutrition

There are no comments on this title.

to post a comment.