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A COMPARATIVE STUDY ON THE HYPOGLYCEMIC EFFECTS OF AMPALAYA TEA (MEMORDICA CHARANTIA) AND GLIBENCLAMIDE ON BLOOD GLUCOSE LEVELS OF MALE SWISS MICE

By: Contributor(s): Language: English Producer: 2002Description: 23 NO. OF PAGESContent type:
  • Text
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  • Unmediated
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LOC classification:
  • THE M-PHAR 2002 0013
Dissertation note: Pharmacology Thesis Summary: The study was intended to determine the hypoglycemic activity of Ampalaya Tea on the blood glucose levels of male Swiss mice as compared to a standard oral hypoglycemic drug that is Glibenclamide. 30 male Swiss mice were divided in to 3 groups in which each group will receive orally a different solutions: ) 1 Group A (control) (distilled water; 2) Group B (Glibenclamide; 3) Group C ( Ampalaya Tea. Each group was subjected to Oral Glucose Tolerance Test (OGTT). Results obtained demonstrated a 33.89%, 49.9% average effectivity at 30 minutes, 34.31% at 60 minutes, 27.22%, 11.47% at 90 minutes after administration of the experimental solutions of Glibenclamide (Group B) and Ampalaya Tea (Group C) respectively. Therefore, Ampalaya Tea has a faster onset and shorter duration of action when compared to Glibenclamide which has a slower onset but longer and more sustained duration of action.
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Theses Far Eastern University - Nicanor Reyes Medical Foundation Theses MPHAR20020013 (Browse shelf(Opens below)) Available T000875

Pharmacology Thesis

The study was intended to determine the hypoglycemic activity of Ampalaya Tea on the blood glucose levels of male Swiss mice as compared to a standard oral hypoglycemic drug that is Glibenclamide. 30 male Swiss mice were divided in to 3 groups in which each group will receive orally a different solutions: ) 1 Group A (control) (distilled water; 2) Group B (Glibenclamide; 3) Group C ( Ampalaya Tea. Each group was subjected to Oral Glucose Tolerance Test (OGTT). Results obtained demonstrated a 33.89%, 49.9% average effectivity at 30 minutes, 34.31% at 60 minutes, 27.22%, 11.47% at 90 minutes after administration of the experimental solutions of Glibenclamide (Group B) and Ampalaya Tea (Group C) respectively. Therefore, Ampalaya Tea has a faster onset and shorter duration of action when compared to Glibenclamide which has a slower onset but longer and more sustained duration of action.

Department of Pharmacology

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