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Catastrophic antiphospholipid antibody syndrome in a 36-year old female with systemic lupus erythematosus / Maria Frances Noreen C. De Leon.

By: Language: English Publication details: Fairview, Quezon City Department of Internal Medicine, FEU-NRMF, 2018Description: photos (black and white); (in folder)Content type:
  • rdacontent
Media type:
  • rdamedia
Carrier type:
  • rdacarrier
LOC classification:
  • MED20180005
Summary: ABSTRACT: Antiphospholipid syndrome (APS) is a multisystem autoimmune condition characterized by vascular thromboses and/or pregnancy loss associated with persistently positive antiphospholipid antibodies (aPL). Catastrophic APS (CAPS) is the most severe form of APS with multiple organ involvement developing over a short period of time, usually associated with microthromnosis. This is a case of a 36-year old female with history of 2 pregnancy losses, admitted due to right upper quadrant pain and subsequently developed multisytemic organ failure. Patient presented with cerebrovascular infract, pleural effusion, renal failure, heart failure, and psychosis with positive titers for lupus anticoagulant and ANA. Refractory to pulse therapy and anticoagulation, rituximab regimen was then initiated which showed significant improvement in patient's condition.
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Item type Current library Call number Status Date due Barcode
Research Far Eastern University - Nicanor Reyes Medical Foundation Research MED20180005 (Browse shelf(Opens below)) Available R000603

Includes bibliographical references.

ABSTRACT: Antiphospholipid syndrome (APS) is a multisystem autoimmune condition characterized by vascular thromboses and/or pregnancy loss associated with persistently positive antiphospholipid antibodies (aPL). Catastrophic APS (CAPS) is the most severe form of APS with multiple organ involvement developing over a short period of time, usually associated with microthromnosis. This is a case of a 36-year old female with history of 2 pregnancy losses, admitted due to right upper quadrant pain and subsequently developed multisytemic organ failure. Patient presented with cerebrovascular infract, pleural effusion, renal failure, heart failure, and psychosis with positive titers for lupus anticoagulant and ANA. Refractory to pulse therapy and anticoagulation, rituximab regimen was then initiated which showed significant improvement in patient's condition.

Research - Department of Medicine

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