Association of factors with the use of oxytocin combined with other uterotonics versus oxytocin alone in the prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019. / [principal investigator]: Dosado, Odessa L. [co-author]: Reyes, Lylah D.

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Language: English Publication details: fairview, Quezon City: Department of OBgyne, FEU-NRMF, 2023Description: (in folder) with flash drive (soft copy)Content type:

text

Media type:

unmediated

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volume

LOC classification:

OB 2023 0004

Summary: ABSTRACT Background: Active Management of Third Stage of Labor (AMTSL), includes prompt administration of uterotonic agents after delivery with oxytocin as first line agent to prevent uterine atony. However, there is an increasing trend with use of combination uterotonics for prevention of uterine atony even among low risk women. Objective: Determine the association of factors with the use of oxytocin combined with other uterotonics and oxytocin alone in prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019 Methods: A four-year cross-sectional study which reviewed charts of women who delivered and were given single or combination uterotonics postpartum. Purposive sampling done. Analysis conducted separately for vaginal delivery and cesarean section. Data extracted included maternal- and obstetric-related factors, as well as uterotonic used and its adverse effects. Result: There were 450 charts of women with singleton pregnancies reviewed, 58.2% (262) had vaginal delivery while 41.7% (188) delivered by cesarean section. Combined uterotonics given to 42.4% (192) of cases, mostly among cesarean deliveries at 82.3% (158/192). Vaginal delivery cases with combined uterotonics showed significantly lower proportion of women with normal preoperative hematocrit (p 0.01). While for cesarean section, use of combined uterotonics was significantly higher among women with blood loss > 500 mL. No adverse effects and history of postpartum hemorrhage recorded. Conclusion: Combined uterotonics was commonly used for cesarean delivery. Factors associated the use of combined uterotonics in prevention of postpartum hemorrhage includes greater estimated blood loss and normal pre- operative hematocrit. Keywords: Uterotonics, Combination uterotonics, Oxytocin, Uterine atony, Postpartum hemorrhage.

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Item type	Current library	Call number	Status	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation	OB 2023 0004 (Browse shelf(Opens below))	Available		R000757

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Previous	OB 2023 0002 A Comparative study on the effects of carbonyl iron and ferrous sulfate in the prevention of iron deficiency anemia among high-risk pregnant women seen at the out-patient department of a tertiary medical center in 2019 to 2020 / [principal investigator]: Lim, Ivy Grace C. [co-author]: Reyes, Lylah D.	OB 2023 0003 Accuracy of Ovarian-Adnexal Reporting and Data System (O-RADS) scoring system in the diagnosis of malignant adnexal masses among cases seen at a tertiary medical center / [primary investigator]: Garcia-Ramos, Dhanielle E. [co-author]: Castro, Abigail Elsie DG., Reyes, Lylah D., Go-Palomar, Cherry	OB 2023 0003 Factors affecting the turnaround time at the emergency room for obstetrics and gynecology patients in a tertiary hospital in Fairview, Quezon city. / [principal investigator]: Lopez-Caritativo, Amier Dayle A.	OB 2023 0004 Association of factors with the use of oxytocin combined with other uterotonics versus oxytocin alone in the prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019. / [principal investigator]: Dosado, Odessa L. [co-author]: Reyes, Lylah D.	OB 2023 0005 Pregnancy outcomes of Subchorionic Hemorrhage during the 1st trimester among women with uncomplicated pregnancies seen at a Tertiary Medical Center from 2018 to 2021. / [principal investigator]: Chin, Ayessa A. [co-author]: Reyes, Lylah D.	OB 2023 0006 Effects of Oral Dydrogesterone and Oral Medroxyprogesterone Acetate in the Treatment of Abnormal Uterine Bleeding-Ovulatory Dysfunction in ReproductiveAged Women from 18 to 39 years old: A Five-Year Chart Review / [author]: Palabrica, Nicolette Vanesa L. [co-author]: Reyes, Lylah D.	OB 2024 0001 One big transition: three cases of malignant transformation of mature cystic teratoma / [author]: Popen-Rono, Onelth Dec A. [co-authors]: Castro, Abigail Elsie DG., Duenas, Rommel Z.	Next

Includes bibliographical refernces.

ABSTRACT
Background: Active Management of Third Stage of Labor (AMTSL), includes prompt administration of uterotonic agents after delivery with oxytocin as first line agent to prevent uterine atony. However, there is an increasing trend with use of combination uterotonics for prevention of uterine atony even among low risk women.
Objective: Determine the association of factors with the use of oxytocin combined with other uterotonics and oxytocin alone in prevention of primary postpartum hemorrhage in a tertiary medical center from 2016 to 2019
Methods: A four-year cross-sectional study which reviewed charts of women who delivered and were given single or combination uterotonics postpartum. Purposive sampling done. Analysis conducted separately for vaginal delivery and cesarean section. Data extracted included maternal- and obstetric-related factors, as well as uterotonic used and its adverse effects.
Result: There were 450 charts of women with singleton pregnancies reviewed, 58.2% (262) had vaginal delivery while 41.7% (188) delivered by cesarean section. Combined uterotonics given to 42.4% (192) of cases, mostly among cesarean deliveries at 82.3% (158/192). Vaginal delivery cases with combined uterotonics showed significantly lower proportion of women with normal preoperative hematocrit (p 0.01). While for cesarean section, use of combined uterotonics was significantly higher among women with blood loss > 500 mL. No adverse effects and history of postpartum hemorrhage recorded.
Conclusion: Combined uterotonics was commonly used for cesarean delivery. Factors associated the use of combined uterotonics in prevention of postpartum hemorrhage includes greater estimated blood loss and normal pre- operative hematocrit.
Keywords: Uterotonics, Combination uterotonics, Oxytocin, Uterine atony, Postpartum hemorrhage.

Department of Obstetrics & Gynecology Research - Department of Obstetrics & Gynecology

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