Suspected rocuronium anaphylaxis : a case report / Rodolfo DR. Astrologio.

Contributor(s):

Astrologio, Rodolfo DR., MD [author]

Language: english Publication details: Fairview, Quezon City: Department of Anesthesiology, FEU-NRMF, 2011.Description: tables; (in folder)Content type:

text

Media type:

unmediated

Carrier type:

volume

LOC classification:

ANES 2011 0002

Summary: Abstract: Anaphylaxis during anesthesia is a rare event which can have dramatic and unpredictable consequences. In 60-70% of cases. It is secondary to neuromuscular blocking agents (NMBAs). The worst manifestations include cardiovascular collapse, brochospasm and laryngeal edema. The overall incidence of perioperative anaphylaxis is estimated at 1 in 10,000-20,000 anesthetic procedures, whereas it is estimated at 1 in 6,500 administrations of NMBAs. Correct management of anaphylaxis during anesthesia requires a multidisciplinary approach with prompt recognition and treatment of the acute event by the attending anesthesiologist. Presented is a case of a 43 year old male who underwent Emergency Exploratory Laparotomy under general anesthesia. The patient had no history of allergies and had never undergone general anesthesia before. After the patient was induced and intubated, he was given Rocuronium for muscle relaxation. Approximately ten minutes after rocuronium administration, tachycardia, O2 desaturation and hypotension were noted. The patient was then given Ephedrine and hyrodcostisone and was shifted to Atracurium after a few more episodes of hypoxia and tachycardia upon administration of Rocuronium. After the patient was stabiilized, surgery resumed without complications.

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Item type	Current library	Call number	Status	Date due	Barcode
Room Use	Far Eastern University - Nicanor Reyes Medical Foundation Research	ANES 2011 0002 (Browse shelf(Opens below))	Available		R000021

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Previous	ANES 2010 0005 A Comparative database report on patient safety culture of the surgical departments in FEU-NRMF Medical Center /	ANES 2010 0006 Effect of patient information leaflet regarding pain relief during labor and delivery on patients' anxiety and satisfaction during preoperative period /	ANES 2011 0001 Carbon dioxide narcosis in respiratory failure : a case report /	ANES 2011 0002 Suspected rocuronium anaphylaxis : a case report /	ANES 2012 0001 Airway management in a patient with penetrating thoracic spine injury /	ANES 2012 0002 A Rare that can scare : a case report on anesthetic management in difficult endotracheal intubation in a 25 year old male patient with epiglottic cyst /	ANES 2012 0003 Case report : anesthetic considerations and management for a patient with a large anterior mediastinal mass /	Next

Includes bibliographical references and appendices

Abstract: Anaphylaxis during anesthesia is a rare event which can have dramatic and unpredictable consequences. In 60-70% of cases. It is secondary to neuromuscular blocking agents (NMBAs). The worst manifestations include cardiovascular collapse, brochospasm and laryngeal edema. The overall incidence of perioperative anaphylaxis is estimated at 1 in 10,000-20,000 anesthetic procedures, whereas it is estimated at 1 in 6,500 administrations of NMBAs. Correct management of anaphylaxis during anesthesia requires a multidisciplinary approach with prompt recognition and treatment of the acute event by the attending anesthesiologist. Presented is a case of a 43 year old male who underwent Emergency Exploratory Laparotomy under general anesthesia. The patient had no history of allergies and had never undergone general anesthesia before. After the patient was induced and intubated, he was given Rocuronium for muscle relaxation. Approximately ten minutes after rocuronium administration, tachycardia, O2 desaturation and hypotension were noted. The patient was then given Ephedrine and hyrodcostisone and was shifted to Atracurium after a few more episodes of hypoxia and tachycardia upon administration of Rocuronium. After the patient was stabiilized, surgery resumed without complications.

Research - Department of Anesthesiology

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